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2,2,6,6-Tetramethylpiperidine

CAS 768-66-1C9H19NAcids & Bases

2,2,6,6-Tetramethylpiperidine (CAS: 768-66-1, C9H19N) is a sterically hindered secondary amine with a molecular weight of 141.25 g/mol. It serves as a valuable building block in organic synthesis. Its hindered nature makes it a useful intermediate for creating specialised chemical compounds and reagents, particularly in the development of polymers, pharmaceuticals, and agricultural chemicals. It is supplied by Tech Serve Solutions with an assay of ≥97.0%.

Synonyms
6-Tetramethylpiperidine768-66-1C9H19N
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2,2,6,6-Tetramethylpiperidine (C9H19N) — chemical structure, CAS 768-66-1; Chemistry, fine chemical supplied by Tech Serve Solutions
Acids & BasesBasesChemical SynthesisOrganic BasesSynthetic Reagents
01 /Applications

Hindered Amine Synthesis

2,2,6,6-Tetramethylpiperidine is a key intermediate in the synthesis of hindered amine light stabilizers (HALS). These compounds protect polymers from degradation caused by UV light and thermal oxidation.

Organic Synthesis Reagent

This compound functions as a sterically hindered base in various organic reactions. Its bulkiness can promote specific reaction pathways and improve selectivity in complex syntheses.

Pharmaceutical Intermediates

It is used as a precursor in the development of active pharmaceutical ingredients (APIs). The tetramethylpiperidine moiety can be incorporated into drug molecules to influence their pharmacokinetic properties.

Catalyst Development

The unique structural features of 2,2,6,6-Tetramethylpiperidine lend themselves to applications in catalyst design, particularly for reactions requiring controlled basicity or specific steric environments.

02 /Properties
Molecular weight141.25
Empirical formulaC9H19N
Assay≥97.0% (GC)
Boiling point152 °C(lit.)
Density0.837 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.445(lit.)n20/D 1.445
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Toxic (GHS06)
Toxic
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H301Toxic if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P301IF SWALLOWED
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point24 °C / 75.2 °F
Transport (UN / ADR)UN 1992 3/PG 3
Water hazard class (WGK, DE)2
Hazard codes (EU)Xn
Risk statements (R)10-22-36/37/38
Safety statements (S)26

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
768-66-1
MDL number
MFCD00005985
PubChem substance
24888966
Beilstein registry
103296
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2,2,6,6-Tetramethylpiperidine used for?

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2,2,6,6-Tetramethylpiperidine is primarily used as a sterically hindered base and a key intermediate in organic synthesis, particularly for producing hindered amine light stabilizers (HALS), pharmaceutical intermediates, and in the development of specialised reagents and catalysts.

What is the CAS number and molecular formula for 2,2,6,6-Tetramethylpiperidine?

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The CAS number for 2,2,6,6-Tetramethylpiperidine is 768-66-1, and its molecular formula is C9H19N.

What grade and purity does Tech Serve Solutions supply for 2,2,6,6-Tetramethylpiperidine?

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Tech Serve Solutions supplies 2,2,6,6-Tetramethylpiperidine with an assay of ≥97.0% (GC). This is a technical/research grade; TSS does not represent it as USP/BP/EP.

How should 2,2,6,6-Tetramethylpiperidine be handled safely?

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Handling 2,2,6,6-Tetramethylpiperidine requires caution due to its flammability and toxicity. It is classified as Danger with hazards including flammability (H226), acute toxicity (H301), skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Always use appropriate personal protective equipment, including safety goggles, gloves, and a respirator, and work in a well-ventilated area, preferably a fume hood.

Can Tech Serve Solutions export 2,2,6,6-Tetramethylpiperidine globally?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 2,2,6,6-Tetramethylpiperidine, serving customers worldwide.

How can I request a sample or a quote for 2,2,6,6-Tetramethylpiperidine?

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To request a sample or a quote for 2,2,6,6-Tetramethylpiperidine, please contact our sales department directly through the website or by phone. Our team will be happy to assist you with your specific requirements.

Need 2,2,6,6-Tetramethylpiperidine in a specific grade or volume?