1,8-Diazabicyclo[5.4.0]undec-7-ene
1,8-Diazabicyclo[5.4.0]undec-7-ene (CAS 6674-22-2), a bicyclic amidine with the formula C9H16N2 and a molecular weight of 152.24 g/mol, is a strong, non-nucleophilic organic base. It serves as a versatile reagent in organic synthesis, particularly in base-catalysed reactions such as esterifications, transesterifications, and Michael additions. DBU is also employed in polymer chemistry and as a catalyst in various chemical transformations.
- IUPAC
- 2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepine,DBU
- Synonyms
- 2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepineDBU
![1,8-Diazabicyclo[5.4.0]undec-7-ene (C9H16N2) — chemical structure, CAS 6674-22-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F6674-22-2.png&w=3840&q=75)
Organic Synthesis Reagent
1,8-Diazabicyclo[5.4.0]undec-7-ene is widely used as a strong, non-nucleophilic base in numerous organic reactions, including elimination, dehydrohalogenation, and condensation reactions. Its utility extends to catalysing the formation of carbon-carbon and carbon-heteroatom bonds.
Catalysis
This compound acts as an effective catalyst in various chemical transformations, such as epoxide ring-opening reactions and the synthesis of polyurethane foams. Its basicity allows it to promote a range of catalytic processes efficiently.
Polymer Chemistry
DBU finds application in polymerisation processes, notably as a catalyst or co-catalyst in the production of specific polymers and resins. It can initiate or accelerate polymer formation reactions.
| Molecular weight | 152.24 |
|---|---|
| Empirical formula | C9H16N2 |
| Assay | ≥98.0% (GC) |
| Boiling point | 115 °C/11 mmHg(lit.) |
| Density | 1.019 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.523 |
| Concentration | 1 M in ethyl acetate |


Hazard statements
- H290May be corrosive to metals
- H301Toxic if swallowed
- H314Causes severe skin burns and eye damage
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 116 °C / 240.8 °F |
| Transport (UN / ADR) | UN 3267 8 / PGII |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | C |
| Risk statements (R) | 22-34-52/53 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,8-Diazabicyclo[5.4.0]undec-7-ene used for?
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1,8-Diazabicyclo[5.4.0]undec-7-ene is primarily used as a strong, non-nucleophilic organic base in organic synthesis, catalysis, and polymer chemistry. It is effective in promoting elimination reactions, esterifications, and Michael additions.
What is the CAS number and molecular formula for 1,8-Diazabicyclo[5.4.0]undec-7-ene?
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The CAS number for 1,8-Diazabicyclo[5.4.0]undec-7-ene is 6674-22-2. Its molecular formula is C9H16N2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,8-Diazabicyclo[5.4.0]undec-7-ene with an assay of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
How should 1,8-Diazabicyclo[5.4.0]undec-7-ene be handled safely?
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1,8-Diazabicyclo[5.4.0]undec-7-ene is classified as Corrosive and Toxic. It causes severe skin burns and eye damage, is harmful if swallowed, and is harmful to aquatic life with long-lasting effects. Always handle with appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area.
How is this chemical packed and exported?
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This product is packed in accordance with transport regulations (UN 3267 8 / PGII) and is available for global export by Tech Serve Solutions.
How can I request a sample or quote?
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To request a sample or a quotation for 1,8-Diazabicyclo[5.4.0]undec-7-ene, please contact our sales team through the TSS website or direct inquiry channels.
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