5-Sulfosalicylic acid dihydrate
5-Sulfosalicylic acid dihydrate (CAS 5965-83-3) is a white crystalline solid with the linear formula HO3SC6H3-2-(OH)CO2H·2H2O and a molar mass of 254.21 g/mol. Also known as sulfosalicylic acid or 2-hydroxy-5-sulfobenzoic acid, it is a water-soluble aromatic sulfonic acid valued as a protein-precipitating reagent, a metal-ion chelator and a versatile organic building block. Tech Serve Solutions supplies it as an ACS reagent grade for analytical and research use worldwide.
- IUPAC
- 2-Hydroxy-5-sulfobenzoic acid
- Synonyms
- Sulfosalicylic acid5-Sulfosalicylic acid5-Sulfosalicylic acid dihydrate2-Hydroxy-5-sulfobenzoic acid3-Carboxy-4-hydroxybenzenesulfonic acid2-Hydroxybenzoic-5-sulfonic acidSalicylsulfonic acid5-Sulfosalicylsyre5-Sulfosalicylsaeure
Protein determination in urine
5-Sulfosalicylic acid is a classic precipitating agent used in clinical and laboratory urinalysis to detect and quantify urinary protein. Its turbidimetric reaction with proteins underpins routine qualitative and semi-quantitative protein assays.
TLC spray reagent for amino acids
It serves as a spray reagent for the detection of amino acids on thin-layer chromatography (TLC) plates. This makes it a convenient visualisation aid in separation and analytical chemistry.
Metal-ion chelation and complexometry
The compound is a well-documented chelating agent that forms coloured complexes with iron(III) and other metal ions. It is therefore used in complexometric and spectrophotometric methods for metal-ion analysis.
Doping agent for conductive polymers
5-Sulfosalicylic acid is employed as a doping agent for polyaniline and related conductive polymers. The sulfonic acid functionality supports proton doping that influences the polymer's conductivity.
Organic synthesis building block
As an aromatic acid bearing carboxyl, hydroxyl and sulfonic acid groups, it acts as a multifunctional building block and synthetic reagent in chemical synthesis and materials research.
| Molecular weight | 254.21 |
|---|---|
| Linear formula | HO3SC6H3-2-(OH)CO2H·2H2O |
| Assay | ≥99%99.0-101.0% (ACS specification) |
| Grade | ACS reagent |
| Impurities tested | ≤0.02% insolubles≤0.04% salicylic acid |
| Application | Spray reagent for the detection of amino acids on TLC plates.1 Doping agent for polyaniline.,Used in urine tests to determine urine protein content |
| Melting point | 105-110 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
| Cation traces | Fe: ≤0.001%heavy metals: ≤0.002% |
| Anion traces | chloride (Cl-): ≤0.001%sulfate (SO42-): ≤0.02% |
| Ignition residue | ≤0.1% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | white crystalline powder |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 5-Sulfosalicylic acid dihydrate used for?
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It is used mainly as a protein-precipitating reagent for determining protein in urine, as a spray reagent for detecting amino acids on TLC plates, as a metal-ion chelator that forms coloured complexes with iron(III), and as a doping agent for polyaniline. It also serves as a multifunctional building block in organic synthesis.
What is the CAS number and molecular formula of 5-Sulfosalicylic acid dihydrate?
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The CAS number is 5965-83-3 and the linear formula is HO3SC6H3-2-(OH)CO2H·2H2O. Its molecular weight is 254.21 g/mol. Related identifiers include EC number 202-555-6, MDL MFCD00149540 and Beilstein registry 650741. It is also known as 2-hydroxy-5-sulfobenzoic acid.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 5-Sulfosalicylic acid dihydrate as an ACS reagent grade material with an assay of not less than 99% (99.0-101.0% to the ACS specification), presented as a white crystalline powder. Specified limits include not more than 0.04% salicylic acid and not more than 0.02% insolubles. We can confirm the exact specification against the current batch certificate of analysis on request.
What are the safety and handling requirements for 5-Sulfosalicylic acid dihydrate?
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It is classified under GHS with the signal word Warning and pictogram GHS07. The hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Avoid breathing dust, wear gloves and eye protection, and in case of eye contact rinse cautiously with water for several minutes (P261, P305+P351+P338). It is assigned German water hazard class WGK 3. Always consult the Safety Data Sheet before use.
How is 5-Sulfosalicylic acid dihydrate packed, shipped and exported?
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It is supplied in tightly closed, moisture-resistant containers sized to laboratory and bulk requirements, with packaging and labelling prepared for compliant international export. As an experienced exporter, Tech Serve Solutions arranges documentation and shipment to customers worldwide; packing details and lead times are confirmed at the time of quotation.
How do I request a sample or quote for 5-Sulfosalicylic acid dihydrate?
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Contact Tech Serve Solutions with your required quantity, grade and destination, and our team will respond with availability, packing options and a formal quotation. Samples can be discussed for qualified applications, and a current certificate of analysis is available on request.
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