2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide
2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide (CAS 86608-70-0) is a vital Wittig reagent with the molecular formula C23H24BrO2P and a molecular weight of 443.31 g/mol. This compound serves as a key reactant in C-C bond formation and olefination reactions, facilitating the synthesis of complex organic molecules. It is widely employed in chemical synthesis for producing advanced materials and pharmaceutical intermediates, offering reliable performance in demanding applications.
- Synonyms
- C23H24BrO2P
Wittig Olefination
This phosphonium salt is a valuable reagent for performing Wittig olefination reactions. It enables the efficient formation of carbon-carbon double bonds, a fundamental transformation in organic synthesis.
Ligand Synthesis for Histamine Receptors
It serves as a precursor in the preparation of specialized ligands designed for histamine receptor binding. The synthesis aims for selectivity towards H3 and H4 subtypes, important in pharmacological research.
Dual Phosphodiesterase-4 and Serotonin Reuptake Inhibitor Synthesis
The compound is utilized in the synthetic pathways leading to dual inhibitors targeting both phosphodiesterase-4 and serotonin reuptake mechanisms, relevant for therapeutic development.
| Molecular weight | 443.31 |
|---|---|
| Empirical formula | C23H24BrO2P |
| Assay | 97% |
| Application | Reactant for:• Wittig olefination1• Preparationof ligands for histamine receptor binding with H3/H4 subtype selectivity2• Preparation of dual inhibitors of phosphodiesterase-4 and serotonin reuptake3 |
| Melting point | 144-146 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
- H373May cause damage to organs through prolonged exposure
- H412Harmful to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-33-41-52/53 |
| Safety statements (S) | 22-26-39-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide used for?
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This compound is primarily used as a Wittig reagent for olefination reactions and in the preparation of ligands for histamine receptor binding, as well as dual inhibitors of phosphodiesterase-4 and serotonin reuptake.
What are the CAS number and formula for this chemical?
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The CAS number is 86608-70-0, and the empirical formula is C23H24BrO2P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is not represented as USP, BP, or EP grade.
How should 2-(1,3-Dioxolan-2-yl)ethyltriphenylphosphonium bromide be handled?
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Handle with care, wearing a dust mask (type N95 US), eyeshields, and gloves. It is harmful if swallowed, causes serious eye damage, may cause damage to organs through prolonged or repeated exposure, and is harmful to aquatic life with long lasting effects.
Can this chemical be exported?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or a sample for this product.
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