(1S,2R)-(+)-trans-2-(1-Methyl-1-phenylethyl)cyclohexanol
(1S,2R)-(+)-trans-2-(1-Methyl-1-phenylethyl)cyclohexanol (CAS: 109527-45-9) is a chiral alcohol with a molecular weight of 218.33 g/mol. This cyclohexyl-based compound functions as a valuable chiral auxiliary in asymmetric synthesis. It is recognised for its ability to induce high levels of stereoselectivity in various chemical transformations, often comparable or superior to other common auxiliaries like menthol derivatives. Supplied by TSS for research and chemical synthesis.
- Synonyms
- C6H5C(CH3)2C6H10OH
Chiral Auxiliary in Asymmetric Synthesis
This compound serves as an effective chiral auxiliary, facilitating stereoselective control in organic reactions. Its unique structure allows for significant asymmetric induction, making it suitable for the synthesis of enantiomerically pure compounds.
Organic Synthesis Building Block
As an organic building block, it provides a chiral scaffold for constructing complex molecules. It is particularly useful in academic research and industrial process development for creating stereochemically defined intermediates.
Reagent for Stereoselective Reactions
Used in academic and industrial laboratories to achieve high enantiomeric excess in a range of chemical transformations. Its efficacy has been documented in studies involving various catalytic and stoichiometric reactions.
| Molecular weight | 218.33 |
|---|---|
| Linear formula | C6H5C(CH3)2C6H10OH |
| Assay | 98% |
| Boiling point | 300 °C(lit.) |
| Density | 1.008 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.541(lit.) |
| Optical activity | [α]24/D +29°, c = 1.7 in methanol |
| Application | Cyclohexyl-based chiral auxiliary that provides equal or greater levels of asymmetric induction when compared to menthol or 8-phenylmenthol in a variety of reactions.1,2,3,4 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | >113 °C / >235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1S,2R)-(+)-trans-2-(1-Methyl-1-phenylethyl)cyclohexanol used for?
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(1S,2R)-(+)-trans-2-(1-Methyl-1-phenylethyl)cyclohexanol is primarily used as a chiral auxiliary in asymmetric synthesis to control stereoselectivity in chemical reactions, and as a chiral building block in organic synthesis.
What is the CAS number and chemical formula for this product?
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The CAS number is 109527-45-9. The linear formula is C6H5C(CH3)2C6H10OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 98%. This is a technical grade suitable for research and chemical synthesis. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the primary safety and handling considerations?
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Appropriate personal protective equipment, including eyeshields and gloves, should be used when handling this chemical. It has a flash point above 113 °C (235.4 °F). Refer to the Safety Data Sheet for comprehensive safety information.
How is this chemical packed and shipped?
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Products are carefully packed according to international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a quote or sample?
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To request a quote or a sample, please use the contact form on our website or contact our sales department directly with your inquiry.
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