(1R)-(−)-Neomenthyl acetate

CAS 146502-80-9C12H22O2Chemical Synthesis

(1R)-(−)-Neomenthyl acetate (CAS: 146502-80-9, Formula: C12H22O2, MW: 198.30) is a chiral ester utilized in asymmetric synthesis. Its distinct optical activity, measured at [α]20/D −48°, makes it a valuable chiral building block in organic synthesis. This compound is supplied by Tech Serve Solutions with a high assay of 99%, suitable for advanced chemical research and manufacturing processes requiring enantiopure materials.

IUPAC: (−)-(1R,2R,5S)-Neomenthyl acetate

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(1R)-(−)-Neomenthyl acetate (C12H22O2) — chemical structure, CAS 146502-80-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksEstersOrganic Building Blocks

01 /Applications

Chiral Auxiliary in Asymmetric Synthesis

(1R)-(−)-Neomenthyl acetate serves as a chiral auxiliary, enabling the stereoselective synthesis of complex organic molecules. Its predictable stereochemical influence aids in controlling the formation of new chiral centres.

Building Block for Chiral Compounds

As a chiral building block, this acetate derivative can be incorporated into larger molecular structures. It is particularly useful for creating enantiomerically pure pharmaceutical intermediates and fine chemicals.

Ester Synthesis and Derivatization

The ester functionality allows for various chemical transformations, including hydrolysis and transesterification, facilitating the synthesis of other chiral derivatives or related compounds.

02 /Properties

Molecular weight	198.30
Empirical formula	C12H22O2
Assay	99%
Boiling point	81 °C/3 mmHg(lit.)
Density	0.912 g/mL at 25 °C(lit.)
Optical activity	[α]20/D −48°, c = 8 in benzene
Melting point	36-38 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Flammable (GHS02) — Flammable

Danger

Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat, sparks and open flames. No smoking

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Transport (UN / ADR)	UN 1325 4.1 / PGII
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

146502-80-9

MDL number

MFCD00062976

Beilstein registry

1909420

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1R)-(−)-Neomenthyl acetate used for?

It is primarily used as a chiral building block and auxiliary in asymmetric synthesis to create enantiomerically pure organic compounds, including pharmaceutical intermediates.

What are the CAS number and formula for (1R)-(−)-Neomenthyl acetate?

The CAS number is 146502-80-9 and the empirical formula is C12H22O2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (1R)-(−)-Neomenthyl acetate with an assay of 99%. TSS does not represent this product as USP, BP, or EP grade.

What are the main safety hazards associated with (1R)-(−)-Neomenthyl acetate?

(1R)-(−)-Neomenthyl acetate is a flammable solid (H228) and requires careful handling. It is classified under GHS02 with a Danger signal word. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator, should be used.

How is this product shipped and exported?

This product is shipped under UN 1325, Class 4.1, Packing Group II. Tech Serve Solutions is a global supplier and exporter experienced in handling such materials.