(1R)-(−)-Menthyl chloroformate

CAS 14602-86-9C11H19ClO2Chemical Synthesis

(1R)-(−)-Menthyl chloroformate (CAS: 14602-86-9, Formula: C11H19ClO2) is a chiral chemical compound with a molecular weight of 218.72 g/mol. Utilised as a vital chiral derivatising agent, it plays a key role in the enantiomeric resolution of alcohols and amines. This reagent is particularly valuable in analytical chemistry for methods employing Gas Chromatography (GC) and High-Performance Liquid Chromatography (HPLC), as well as in classical resolution by crystallisation.

IUPAC: (−)-Menthyl chloroformate

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(1R)-(−)-Menthyl chloroformate (C11H19ClO2) — chemical structure, CAS 14602-86-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Acid HalidesAnalytical ReagentsAnalytical/ChromatographyAsymmetric SynthesisChemical SynthesisChiral Building BlocksChiral Resolution ReagentsChiral Resolving ReagentsDerivatization ReagentsDerivatization Reagents HPLC

01 /Applications

Chiral Derivatisation Agent

Serves as a critical reagent for forming diastereomeric derivatives of chiral alcohols and amines. This process is essential for separating and analysing enantiomers using chromatographic techniques like GC and HPLC.

Asymmetric Synthesis

Facilitates the resolution of chiral compounds, contributing to the production of enantiomerically pure substances required in pharmaceuticals and fine chemical synthesis.

Analytical Chemistry Reagent

Employed in analytical laboratories for the accurate determination of enantiomeric excess (ee) and purity. Its application aids in quality control and research involving chiral molecules.

Resolution of Alcohols and Amines

Specifically used to derivatise chiral alcohols and amines, enabling their separation either by chromatographic methods or through selective crystallisation of the resulting diastereomers.

02 /Properties

Molecular weight	218.72
Empirical formula	C11H19ClO2
Boiling point	108-109 °C/11 mmHg(lit.)
Density	1.02 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.458(lit.)
Optical activity	[α]20/D −83°, c = 1 in chloroform
Optical purity	ee: 99% (GLC)
Vapour pressure	0.01 psi (20 °C)
Storage temperature	2-8°C
Application	Chiral derivatizing agent used for the resolution of alcohols and amines by GC, HPLC, or crystallization.1

03 /Safety & handling

GHS hazard pictogram: Corrosive (GHS05) — Corrosive

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H314Causes severe skin burns and eye damage
H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P280Wear protective gloves, clothing and eye/face protection
P305IF IN EYES
P310Immediately call a POISON CENTER or doctor

Protective equipment	Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	70 °C / 158 °F
Transport (UN / ADR)	UN 3277 6.1/PG 2
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T,N
Risk statements (R)	23-34-51/53
Safety statements (S)	26-36/37/39-45-61

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

14602-86-9

MDL number

MFCD00009694

PubChem substance

24854513

Beilstein registry

2414686

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (1R)-(−)-Menthyl chloroformate primarily used for?

(1R)-(−)-Menthyl chloroformate is primarily used as a chiral derivatising agent for the resolution of alcohols and amines via GC, HPLC, or crystallisation.

What is the CAS number and chemical formula for (1R)-(−)-Menthyl chloroformate?

The CAS number is 14602-86-9, and the chemical formula is C11H19ClO2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (1R)-(−)-Menthyl chloroformate with a high optical purity (ee: 99% by GLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade; it is suitable for research and chemical synthesis applications.

What are the safety precautions when handling (1R)-(−)-Menthyl chloroformate?

(1R)-(−)-Menthyl chloroformate is a corrosive and toxic substance. Handle with extreme caution, wearing appropriate personal protective equipment including a full-face respirator, chemical-resistant gloves, and goggles. Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Refer to the safety data sheet for detailed handling and emergency procedures.

How is (1R)-(−)-Menthyl chloroformate packed, shipped, and exported?

Products are securely packed to international standards for safe transit. Tech Serve Solutions is a global supplier and exporter, experienced in shipping fine chemicals worldwide. Specific packaging and shipping details can be provided upon request.

How can I request a quote or sample of (1R)-(−)-Menthyl chloroformate?

To request a quote or a sample, please contact our sales team via the website or email. Provide your contact details and the required quantity for prompt processing.