(1R,2R)-(−)-1,2-Diaminocyclohexane
(1R,2R)-(−)-1,2-Diaminocyclohexane (CAS 20439-47-8) is a chiral diamine with the linear formula C6H10(NH2)2 and a molecular weight of 114.19 g/mol. This compound serves as a crucial chiral building block and ligand in asymmetric synthesis. It is widely employed in the development of stereoselective reactions and the synthesis of complex organic molecules, particularly in pharmaceutical research and fine chemical manufacturing.
- IUPAC
- (1R)-trans-1,2-Cyclohexanediamine
- Synonyms
- 20439-47-8C6H10(NH2)2(1R)-trans-1,2-Cyclohexanediamine
Chiral Ligand in Asymmetric Catalysis
(1R,2R)-(−)-1,2-Diaminocyclohexane is extensively used as a chiral auxiliary and ligand in various transition metal-catalyzed asymmetric reactions, enabling the enantioselective synthesis of valuable compounds.
Building Block for Chiral Amines and Heterocycles
It acts as a fundamental chiral synthon for constructing complex chiral amines and nitrogen-containing heterocyclic compounds, crucial in medicinal chemistry and materials science.
Resolution of Racemic Mixtures
This diamine can be employed as a resolving agent for the separation of enantiomers from racemic mixtures, yielding enantiomerically pure compounds.
| Molecular weight | 114.19 |
|---|---|
| Linear formula | C6H10(NH2)2 |
| Assay | 98% |
| Optical activity | [α]20/D −25°, c = 5 in 1 M HCl |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | 70 °C / 158 °F |
| Transport (UN / ADR) | UN 3259PSN2 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-(−)-1,2-Diaminocyclohexane primarily used for?
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It is primarily used as a chiral building block and ligand in asymmetric synthesis, particularly in organic chemistry and pharmaceutical research for creating stereoselective reactions and enantiomerically pure compounds.
What is the CAS number and chemical formula for (1R,2R)-(−)-1,2-Diaminocyclohexane?
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The CAS number is 20439-47-8 and the linear chemical formula is C6H10(NH2)2.
What grade and purity does Tech Serve Solutions supply for (1R,2R)-(−)-1,2-Diaminocyclohexane?
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Tech Serve Solutions supplies (1R,2R)-(−)-1,2-Diaminocyclohexane with an assay of 98%. This product is not represented as USP, BP, or EP grade.
How should (1R,2R)-(−)-1,2-Diaminocyclohexane be handled safely?
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This compound causes severe skin burns and eye damage (H314). Handle with extreme care, using appropriate personal protective equipment including safety goggles, face shields, and chemical-resistant gloves. Ensure adequate ventilation and refer to the Safety Data Sheet for detailed handling and emergency procedures.
Can Tech Serve Solutions export (1R,2R)-(−)-1,2-Diaminocyclohexane?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (1R,2R)-(−)-1,2-Diaminocyclohexane, serving customers worldwide.
How can I request a quote or sample for (1R,2R)-(−)-1,2-Diaminocyclohexane?
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To request a quote or sample, please contact our sales team through the website or by phone, providing the product name and CAS number (20439-47-8).
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