(1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]ethanediamine
(1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]ethanediamine (CAS: 137944-39-9) is a chiral diamine with the molecular formula C18H18F6N2 and a molecular weight of 376.34 g/mol. It is a high-purity compound, typically supplied at 97% assay. This molecule serves as a valuable building block and ligand in asymmetric synthesis, facilitating the creation of enantiomerically pure compounds for various chemical and pharmaceutical applications. Its specific stereochemistry makes it crucial for stereoselective reactions.
- IUPAC
- (1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[(3-trifluoromethyl)phenyl]-1,2-ethanediamine
- Synonyms
- 2-bis[3-(trifluoromethyl)phenyl]ethanediamine(1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[(3-trifluoromethyl)phenyl]-1,2-ethanediamine
![(1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]ethanediamine (C18H18F6N2) — chemical structure, CAS 137944-39-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F137944-39-9.png&w=3840&q=75)
Asymmetric Synthesis
This chiral diamine is employed as a ligand or catalyst in asymmetric synthesis, enabling the stereoselective formation of chiral molecules. Its structure is conducive to creating specific enantiomers, vital for drug discovery and development.
Chiral Ligand Development
As a sophisticated chiral building block, it is used in the design and synthesis of advanced chiral ligands. These ligands are critical for transition metal-catalyzed asymmetric reactions, improving enantioselectivity and reaction efficiency.
Organic Synthesis Intermediate
It functions as a key intermediate in multi-step organic synthesis pathways. Researchers utilise its unique structural features to construct complex organic molecules with defined stereochemistry.
| Molecular weight | 376.34 |
|---|---|
| Empirical formula | C18H18F6N2 |
| Assay | 97% |
| Optical activity | [α]22/D +18.0°, c = 1 in chloroform |
| Melting point | 112-117 °C |
Hazard statements
- H410Very toxic to aquatic life with long-lasting effects
Precautionary statements
- P273Avoid release to the environment
- P501Dispose of contents and container per local regulations
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3077 9 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50/53 |
| Safety statements (S) | 24/25-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]ethanediamine used for?
+
This compound is primarily used in asymmetric synthesis as a chiral building block and ligand. It facilitates stereoselective reactions for creating enantiomerically pure compounds in chemical and pharmaceutical research.
What are the CAS number and formula for this chemical?
+
The CAS number is 137944-39-9 and the empirical formula is C18H18F6N2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this compound at an assay of 97%. We do not represent it as USP, BP, EP, or any pharmacopoeial grade.
How should (1R,2R)-(+)-N,N′-Dimethyl-1,2-bis[3-(trifluoromethyl)phenyl]ethanediamine be handled?
+
This compound is classified as H410 (Very toxic to aquatic life with long lasting effects). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Avoid release to the environment. Ensure adequate ventilation and use in a designated area.
How is this chemical packed, shipped, and exported?
+
This chemical is classified under UN 3077, Class 9, Packing Group III. It is carefully packed and exported by Tech Serve Solutions, adhering to all relevant international shipping regulations for hazardous materials.
How can I request a sample or quote for this product?
+
Please contact our sales team via the website or direct email to request a sample or a formal quotation for this product.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis