(1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
(1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol (CAS 716-61-0) is a chiral organic building block with the molecular formula HOCH2CH(NH2)CH(C6H4NO2)OH and a molecular weight of 212.20. This compound, also known as Chloramphenicol base, is primarily utilised in asymmetric synthesis and chemical research. Its specific stereochemistry makes it valuable for constructing complex molecules where chirality is critical.
- IUPAC
- D-(−)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol,Chloramphenicol base
- Synonyms
- 716-61-0HOCH2CH(NH2)CH(C6H4NO2)OHChloramphenicol baseD-(−)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol
Asymmetric Synthesis
Serves as a crucial chiral building block for synthesising enantiomerically pure compounds. Its defined stereocentres are essential for stereoselective reactions.
Chemical Research
Employed in academic and industrial research laboratories for exploring new synthetic pathways and developing novel organic molecules. It acts as a versatile intermediate in complex organic synthesis.
Intermediate in Organic Synthesis
Facilitates the creation of more complex chemical structures. Its functional groups (amine and hydroxyls) allow for diverse chemical transformations.
| Molecular weight | 212.20 |
|---|---|
| Linear formula | HOCH2CH(NH2)CH(C6H4NO2)OH |
| Assay | 99% |
| Optical activity | [α]25/D −30°, c = 1 in 6 M HCl |
| Melting point | 163-165 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol used for?
+
(1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is primarily used as a chiral building block in asymmetric synthesis and for general chemical research as an intermediate in organic synthesis.
What is the CAS number and formula for this compound?
+
The CAS number is 716-61-0, and its linear formula is HOCH2CH(NH2)CH(C6H4NO2)OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this chemical with an assay of 99%. We do not represent it as USP, BP, EP, or pharmacopoeia grade unless explicitly stated in the product specifications.
How should (1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol be handled safely?
+
This compound is a Warning substance and may cause harm if swallowed (H302), skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Use a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. Handle in accordance with P261-P305 + P351 + P338.
Is this compound a controlled substance?
+
The provided data does not indicate that this compound is a controlled substance.
How is (1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol shipped or exported?
+
This chemical is classified under UN 3259, Class 8, Packing Group 3, and is exported by Tech Serve Solutions in compliance with all relevant regulations.
How can I request a sample or quote for this chemical?
+
Please contact our sales department via the website or by phone to request a sample or a formal quotation for (1R,2R)-(−)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis