L-(−)-Malic acid
L-(−)-Malic acid (CAS: 97-67-6), with the chemical formula HO2CCH2CH(OH)CO2H and a molecular weight of 134.09 g/mol, is a chiral organic compound. It serves as a selective protecting reagent for amino acid derivatives and a versatile synthon in chemical synthesis. Its applications extend to the preparation of complex molecules, including pharmaceutical intermediates and biologically active compounds. This chemical is supplied by Tech Serve Solutions with a purity of ≥99.0%.
- IUPAC
- (S)-(−)-2-Hydroxysuccinic acid,L-Hydroxybutanedioic acid
- Synonyms
- L-Malic acid(S)-Malic acid(2S)-Hydroxysuccinic acidL-Hydroxybutanedioic acid
Selective Amino Protecting Reagent
L-(−)-Malic acid is employed as a reagent for the selective protection of α-amino groups in amino acid derivatives during complex organic synthesis.
Synthon for Chiral Compound Synthesis
This chiral building block is utilised in the synthesis of various stereochemically defined compounds, such as κ-opioid receptor agonists and vitamin D analogues.
Intermediate for Pharmaceutical Research
It serves as a versatile intermediate in the multi-step synthesis of biologically relevant molecules, including phoslactomycin B, contributing to pharmaceutical research and development.
| Molecular weight | 134.09 |
|---|---|
| Linear formula | HO2CCH2CH(OH)CO2H |
| Assay | ≥99.0% |
| Application | Selective α-amino protecting reagent for amino acid derivatives.1 Versatile synthon for the preparation of chiral compounds including κ-opioid receptor agonists,2 1α,25-dihydroxyvitamin D3 analogue,3 and phoslactomycin B.4 |
| Melting point | 101-103 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-(−)-Malic acid used for?
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L-(−)-Malic acid is used as a selective α-amino protecting reagent for amino acid derivatives and as a versatile synthon for the preparation of chiral compounds.
What is the CAS number and chemical formula for L-(−)-Malic acid?
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The CAS number for L-(−)-Malic acid is 97-67-6, and its chemical formula is HO2CCH2CH(OH)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-(−)-Malic acid with an assay of ≥99.0%. This is a technical/research grade, and TSS does not represent it as USP, BP, or EP grade.
How should L-(−)-Malic acid be handled?
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L-(−)-Malic acid is classified as a warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be worn during handling. Ensure adequate ventilation.
How is L-(−)-Malic acid packed, shipped, and exported?
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L-(−)-Malic acid is carefully packed to maintain its integrity during transit. Tech Serve Solutions, as a global supplier, handles the export of this chemical in compliance with international shipping regulations.
How can I request a sample or quote for L-(−)-Malic acid?
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To request a sample or obtain a quote for L-(−)-Malic acid, please contact our sales team through the website or by phone, providing your specific requirements and shipping details.
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