1H-Indazole-5-boronic acid hydrochloride
1H-Indazole-5-boronic acid hydrochloride (CAS: 1257738-46-7) is a valuable organoboron compound with the molecular formula C7H8BClN2O2. This heteroaryl boronic acid derivative serves as a versatile building block in organic synthesis, particularly in cross-coupling reactions. It is typically supplied for research and development purposes, facilitating the creation of complex molecular architectures in pharmaceutical and chemical research.
Suzuki-Miyaura Cross-Coupling
1H-Indazole-5-boronic acid hydrochloride is an effective coupling partner in Suzuki-Miyaura reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides. This is crucial for synthesizing complex organic molecules.
Organic Synthesis Intermediate
As a functionalized indazole derivative, it is employed as an intermediate in the synthesis of novel compounds. Its boronic acid moiety allows for diverse chemical transformations.
Pharmaceutical Research
This compound is utilised in medicinal chemistry for the development of new drug candidates. The indazole core is present in various biologically active molecules.
| Molecular weight | 198.41 |
|---|---|
| Empirical formula | C7H8BClN2O2 |
| Storage temperature | 2-8°C |
| Melting point | 154-166 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 2 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-Indazole-5-boronic acid hydrochloride used for?
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1H-Indazole-5-boronic acid hydrochloride is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions and in pharmaceutical research for creating novel molecular structures.
What are the CAS number and formula for 1H-Indazole-5-boronic acid hydrochloride?
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The CAS number is 1257738-46-7 and the empirical formula is C7H8BClN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1H-Indazole-5-boronic acid hydrochloride typically as a research-grade chemical. The exact purity is available on the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade.
How should 1H-Indazole-5-boronic acid hydrochloride be handled?
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Handle 1H-Indazole-5-boronic acid hydrochloride with care. It is classified as causing skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Wear appropriate personal protective equipment, including gloves, eye protection, and ensure adequate ventilation.
How is 1H-Indazole-5-boronic acid hydrochloride packed, shipped, and exported?
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This chemical is carefully packed in compliance with international shipping regulations. Tech Serve Solutions has extensive experience in exporting fine chemicals globally.
How can I request a sample or quote for 1H-Indazole-5-boronic acid hydrochloride?
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To request a sample or a quote, please contact our sales department via the website or direct email, providing your specific requirements.
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