1H-Indazole-5-boronic acid pinacol ester
1H-Indazole-5-boronic acid pinacol ester (CAS: 862723-42-0, C13H17BN2O2) is an organoboron compound with a molecular weight of 244.10 g/mol. This versatile building block is primarily utilised in organic synthesis, particularly in cross-coupling reactions for the construction of complex molecules. Its indazole core, functionalised with a boronate ester, makes it a valuable intermediate in pharmaceutical research and development.
- IUPAC
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
- Synonyms
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole
Suzuki-Miyaura Coupling Reactions
This compound serves as a key reactant in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds. It facilitates the introduction of the 1H-indazole moiety into various organic scaffolds.
Pharmaceutical Intermediate
The indazole ring system is a common feature in many biologically active compounds. 1H-Indazole-5-boronic acid pinacol ester is therefore a significant intermediate in the synthesis of potential pharmaceutical agents and drug discovery programmes.
Materials Science
Organoboron compounds, including this ester, can find applications in the development of novel materials, such as organic light-emitting diodes (OLEDs) or functional polymers, owing to their unique electronic and structural properties.
Organic Synthesis Reagent
As a heteroaryl boronate ester, it is a valuable reagent for synthetic chemists seeking to functionalise complex organic molecules with specific nitrogen-containing heterocyclic systems.
| Molecular weight | 244.10 |
|---|---|
| Empirical formula | C13H17BN2O2 |
| Assay | 95% |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1H-Indazole-5-boronic acid pinacol ester used for?
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1H-Indazole-5-boronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions and in the development of pharmaceutical intermediates.
What is the CAS number and chemical formula for 1H-Indazole-5-boronic acid pinacol ester?
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The CAS number is 862723-42-0 and the chemical formula is C13H17BN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1H-Indazole-5-boronic acid pinacol ester with an assay of 95%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should I handle 1H-Indazole-5-boronic acid pinacol ester?
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This compound is a Warning substance with hazards H315 (causes skin irritation), H319 (causes serious eye irritation), and H335 (may cause respiratory irritation). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Can Tech Serve Solutions export 1H-Indazole-5-boronic acid pinacol ester?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and can export 1H-Indazole-5-boronic acid pinacol ester worldwide.
How can I request a sample or quote for 1H-Indazole-5-boronic acid pinacol ester?
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To request a sample or a quote, please visit the Tech Serve Solutions website or contact our sales team directly.
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