(11bR)-(–)-4,4-Dibutyl-4,5-dihydro-2,6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1′,2′-e]azepinium bromide
(11bR)-(–)-4,4-Dibutyl-4,5-dihydro-2,6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1′,2′-e]azepinium bromide (CAS 887938-70-7) is a sophisticated chiral organocatalyst with a molecular weight of 748.64 g/mol. It is recognised for its high efficacy as a phase transfer catalyst in asymmetric synthesis. This compound is primarily employed to facilitate enantioselective reactions, notably the α-alkylation of glycine derivatives with exceptional efficiency and at very low catalytic loadings.
- Synonyms
- 6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1′,2′-e]azepinium bromideC42H36BrF6N
![(11bR)-(–)-4,4-Dibutyl-4,5-dihydro-2,6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1′,2′-e]azepinium bromide (C42H36BrF6N) — chemical structure, CAS 887938-70-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F887938-70-7.png&w=3840&q=75)
Asymmetric α-Alkylation of Glycine Derivatives
This azepinium bromide serves as a potent phase transfer organocatalyst for the asymmetric α-alkylation of glycine derivatives. It enables high enantioselectivity even at extremely low catalyst loadings, making it valuable for chiral building block synthesis.
Chiral Catalysis in Organic Synthesis
As a chiral catalyst, this compound facilitates enantioselective transformations. Its application is crucial in synthesising complex chiral molecules where stereochemical control is paramount, contributing to advancements in pharmaceuticals and fine chemicals.
Phase Transfer Catalysis
The compound functions effectively as a phase transfer catalyst, promoting reactions between reactants located in different immiscible phases. This capability is particularly useful for reactions involving anionic species and organic substrates.
| Molecular weight | 748.64 |
|---|---|
| Empirical formula | C42H36BrF6N |
| Application | Potent phase transfer organocatalyst for asymmetric α-alkylation of glycine derivatives at extremely low loadings.1 |
| Melting point | 223-228 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (11bR)-(–)-4,4-Dibutyl-4,5-dihydro-2,6-bis(3,4,5-trifluorophenyl)-3H-dinaphth[2,1-c:1′,2′-e]azepinium bromide used for?
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This compound is primarily used as a potent phase transfer organocatalyst for the asymmetric α-alkylation of glycine derivatives. It is highly effective for chiral synthesis applications.
What is the CAS number and formula for this azepinium bromide?
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The CAS number is 887938-70-7 and the empirical formula is C42H36BrF6N.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific purity and grade available may vary; please contact us for detailed specifications. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always handle with appropriate personal protective equipment, including gloves, eye protection, and ensure adequate ventilation. Avoid breathing dust/fume/gas/mist/vapours/spray.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions adheres to strict international regulations for the packing, shipping, and export of chemicals, ensuring safe and compliant delivery to our global clients.
How can I request a sample or quote for this product?
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To request a sample or quote, please visit the product page on our website and use the dedicated 'Request a Quote' or 'Sample Request' form, or contact our sales team directly via email or phone.
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