Tech Serve Solutions

1-(Trimethylsilyl)imidazole

CAS 18156-74-6C6H12N2SiChemical Synthesis

1-(Trimethylsilyl)imidazole (CAS 18156-74-6), molecular formula C6H12N2Si, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
N-Trimethylsilylimidazole,TMSI,TSIM
1-(Trimethylsilyl)imidazole
Building BlocksC3 to C8Chemical SynthesisHeterocyclic Building BlocksImidazoles
01 /Properties
Molecular weight140.26
Empirical formulaC6H12N2Si
Assay≥98.0% (T)≥98.0%
Boiling point93-94 °C/14 mmHg(lit.)
Density0.957 g/mL at 20 °C0.956 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.475(lit.)
Storage temperature2-8°C
Application1-(Trimethylsilyl)imidazole (TMSI) was used for derivatization of carbohydrates into trimethylsilyl ethers1. It was also used to synthesize polysubstituted chiral spirotetrahydropyrans2 and as silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.3
02 /Safety & handling
Flammable
Flammable
Harmful / irritant
Harmful / irritant
Danger

Hazard statements

  • H225Highly flammable liquid and vapour
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P210Keep away from heat, sparks and open flames. No smoking
  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point6 °C / 42.8 °F
Transport (UN / ADR)UN 1993BF 3 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)F,Xi
Risk statements (R)11-36/37/38
Safety statements (S)16-26-33

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
18156-74-6
MDL number
MFCD00005280
PubChem substance
24849355
Beilstein registry
606148
04 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

05 /Frequently asked questions

What is 1-(Trimethylsilyl)imidazole?

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1-(Trimethylsilyl)imidazole (CAS 18156-74-6), molecular formula C6H12N2Si, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.

What grades of 1-(Trimethylsilyl)imidazole does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 1-(Trimethylsilyl)imidazole in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of 1-(Trimethylsilyl)imidazole?

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1-(Trimethylsilyl)imidazole has CAS number 18156-74-6 and molecular formula C6H12N2Si. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for 1-(Trimethylsilyl)imidazole?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of 1-(Trimethylsilyl)imidazole ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should 1-(Trimethylsilyl)imidazole be stored?

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Store 1-(Trimethylsilyl)imidazole in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is 1-(Trimethylsilyl)imidazole used for?

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1-(Trimethylsilyl)imidazole is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for 1-(Trimethylsilyl)imidazole?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need 1-(Trimethylsilyl)imidazole in a specific grade or volume?

Request a quote