1-(Trimethylsilyl)pyrrolidine
1-(Trimethylsilyl)pyrrolidine (CAS 15097-49-1) is a silicon-containing heterocyclic compound with the molecular formula C7H17NSi. It functions as a valuable building block in chemical synthesis, particularly within the realm of organic chemistry. Its utility is demonstrated in reactions such as the ring opening of L-serine β-lactone and the preparation of iminium triflate salts, showcasing its versatility in constructing complex molecules.
Ring Opening Reactions
Used in the ring opening of L-serine β-lactone to produce corresponding 5-amino-L-alanine derivatives.
Preparation of Iminium Salts
Employed in the synthesis of iminium triflate salts, important intermediates in organic transformations.
Heterocyclic Synthesis
Serves as a building block for the synthesis of various heterocyclic compounds, including pyrrolidines.
| Molecular weight | 143.30 |
|---|---|
| Empirical formula | C7H17NSi |
| Assay | 97% |
| Boiling point | 139-140 °C(lit.) |
| Density | 0.821 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.433(lit.) |
| Application | 1-(Trimethylsilyl)pyrrolidine (N-trimethylsilyl pyrrolidine) has been used in:• ring opening reaction of L-serine β-lactone to yield corresponding 5-amino-L-alanine derivatives1• the preparation of iminium triflate salts2 |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 4 °C / 39.2 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What are the primary uses of 1-(Trimethylsilyl)pyrrolidine?
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1-(Trimethylsilyl)pyrrolidine is primarily used as a building block in chemical synthesis, notably for ring opening reactions of lactones and the preparation of iminium triflate salts.
What is the CAS number and formula for 1-(Trimethylsilyl)pyrrolidine?
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The CAS number is 15097-49-1, and its empirical formula is C7H17NSi.
What is the purity/grade of 1-(Trimethylsilyl)pyrrolidine offered by TSS?
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We offer 1-(Trimethylsilyl)pyrrolidine with a minimum assay of 97%.
What are the main hazards associated with 1-(Trimethylsilyl)pyrrolidine?
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1-(Trimethylsilyl)pyrrolidine is classified as highly flammable (H225) and causes severe skin burns and eye damage (H314), requiring careful handling and appropriate personal protective equipment.
How is 1-(Trimethylsilyl)pyrrolidine packed and shipped?
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This chemical is packed in accordance with UN 2924 regulations for transportation, classified under hazard class 8(3) with Packing Group II.
How can I request a quote for 1-(Trimethylsilyl)pyrrolidine?
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To request a quote, please contact our sales department via the website or direct email, providing your required quantity and delivery details.
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