1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene
1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene (CAS 40230-95-3) is an organosilicon compound with the molecular formula C<sub>6</sub>H<sub>4</sub>CF<sub>3</sub>C≡CSi(CH<sub>3</sub>)<sub>3</sub> and a molecular weight of 242.31 g/mol. This fluorinated alkynyl compound serves as a valuable building block in organic synthesis, particularly for introducing trifluoromethylphenyl and trimethylsilyl ethynyl moieties into complex molecules. Its properties make it suitable for research and development in material science and medicinal chemistry.
- IUPAC
- [4-(Trifluoromethyl)phenyl](trimethylsilyl)acetylene
- Synonyms
- [4-(Trifluoromethyl)phenyl](trimethylsilyl)acetylene
![1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene (C6H4CF3C≡CSi(CH3)3) — chemical structure, CAS 40230-95-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F40230-95-3.png&w=3840&q=75)
Organic Synthesis Intermediate
Utilised as a key intermediate in the construction of more complex organic molecules. Its trifluoromethyl and silyl-protected alkyne functionalities allow for diverse downstream reactions.
Material Science Research
Investigated for potential applications in the development of novel materials due to the presence of the trifluoromethyl group and the rigid alkynyl linkage.
Medicinal Chemistry Building Block
Serves as a precursor for synthesizing potential drug candidates or pharmaceutical intermediates, where the trifluoromethyl group can enhance lipophilicity and metabolic stability.
| Molecular weight | 242.31 |
|---|---|
| Linear formula | C6H4CF3C≡CSi(CH3)3 |
| Assay | 97% |
| Boiling point | 80 °C/0.1 mmHg(lit.) |
| Density | 1.029 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.4760(lit.) |
Hazard statements
- H226Flammable liquid and vapour
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 57 °C / 134.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene used for?
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This compound is primarily used as a versatile building block in organic synthesis, material science research, and medicinal chemistry for the construction of complex molecules.
What is the CAS number and formula for 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene?
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The CAS number is 40230-95-3, and the linear formula is C<sub>6</sub>H<sub>4</sub>CF<sub>3</sub>C≡CSi(CH<sub>3</sub>)<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product at a purity of 97% (assay). This is a technical/research grade material, and TSS does not represent it as USP, BP, EP, or pharmacopoeia grade.
How should 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene be handled?
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This compound is classified as flammable (H226) and requires careful handling. Recommended personal protective equipment includes eyeshields, gloves, and a half-mask or multi-purpose respirator. Store away from ignition sources.
Is 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene a controlled substance?
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The provided data does not indicate that this compound is a controlled substance.
How is 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene packed, shipped, and exported?
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Products are carefully packed according to international shipping regulations, including UN 1993 classification for flammable liquids, and are exported globally by TSS.
How can I request a sample or quote for 1-[(Trimethylsilyl)ethynyl]-4-(trifluoromethyl)benzene?
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To request a sample or quote, please contact our sales team through the website or direct inquiry channels.
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