1-(tert-Butyldimethylsilyloxy)-2-propanone
1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) is a silyl ether derivative of hydroxyacetone. This organosilicon compound, with a molecular weight of 188.34 g/mol, serves as a valuable intermediate in organic synthesis. Its utility lies in its role as a protected form of hydroxyacetone, allowing for selective reactions at other sites before deprotection. It is commonly employed in chemical synthesis and research laboratories.
Organic Synthesis Intermediate
This compound is primarily used as a building block in the synthesis of more complex organic molecules. The tert-butyldimethylsilyl (TBS) group provides effective protection for the hydroxyl functionality, enabling selective chemical transformations.
Research and Development
As a versatile reagent, 1-(tert-Butyldimethylsilyloxy)-2-propanone finds application in academic and industrial research laboratories for exploring novel synthetic pathways and developing new chemical entities.
Precursor for Specialty Chemicals
It can be employed as a precursor in the multi-step synthesis of various specialty chemicals, pharmaceuticals, and fine chemical products where precise molecular architecture is required.
| Molecular weight | 188.34 |
|---|---|
| Linear formula | (CH3)3CSi(CH3)2OCH2COCH3 |
| Assay | 98% |
| Boiling point | 35-38 °C/0.6 mmHg(lit.) |
| Density | 0.976 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.426(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(tert-Butyldimethylsilyloxy)-2-propanone used for?
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1-(tert-Butyldimethylsilyloxy)-2-propanone (CAS: 74685-00-0) is used as a valuable intermediate and building block in organic synthesis, particularly for constructing complex molecules where a protected hydroxyacetone moiety is required.
What is the CAS number and molecular formula for 1-(tert-Butyldimethylsilyloxy)-2-propanone?
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The CAS number is 74685-00-0. The linear formula is (CH3)3SiCH2COCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-(tert-Butyldimethylsilyloxy)-2-propanone with a minimum purity of 98% (assay). This product is intended for research and technical use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-(tert-Butyldimethylsilyloxy)-2-propanone be handled safely?
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Safe handling requires appropriate personal protective equipment, including eyeshields and gloves. Due to its flammability (flash point 74 °C), it should be kept away from heat and ignition sources. Consult the Safety Data Sheet for detailed handling and emergency procedures. Respiratory protection may be necessary.
How is 1-(tert-Butyldimethylsilyloxy)-2-propanone packed and shipped?
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Products are carefully packed in compliance with international shipping regulations. Tech Serve Solutions is experienced in exporting fine chemicals globally.
How can I request a quote or sample for 1-(tert-Butyldimethylsilyloxy)-2-propanone?
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Please contact our sales team via the website or phone to request a quotation or a sample. Please provide your details and the quantity required.
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