1-Piperonylpiperazine
1-Piperonylpiperazine (CAS: 32231-06-4), a heterocyclic organic compound with the formula C12H16N2O2, has a molecular weight of 220.27 g/mol. This chemical serves as a valuable building block in organic synthesis. It is particularly utilised in the preparation of more complex molecules, with documented use in the synthesis of compounds like acetyl-caffeic acid-1-piperonylpiperazine (HBU-47).

Organic Synthesis Intermediate
1-Piperonylpiperazine functions as a key intermediate in the synthesis of various organic compounds. Its structure allows for versatile chemical modifications, making it useful in constructing complex molecular architectures.
Synthesis of Acetyl-caffeic Acid Derivatives
This compound has been specifically employed in the synthesis of acetyl-caffeic acid-1-piperonylpiperazine (HBU-47). This highlights its role in the development of specific pharmaceutical intermediates or research compounds.
Heterocyclic Chemistry
As a piperazine derivative containing a piperonyl group, it is relevant in heterocyclic chemistry research and development. Its structure is amenable to various reactions common to nitrogen-containing heterocycles.
| Molecular weight | 220.27 |
|---|---|
| Empirical formula | C12H16N2O2 |
| Assay | 97% |
| Boiling point | 147-149 °C/2 mmHg(lit.) |
| Application | 1-Piperonylpiperazine was used in the synthesis of acetyl-caffeic acid-1-piperonylpiperazine (HBU-47)1. |
| Melting point | 36-40 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Piperonylpiperazine used for?
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1-Piperonylpiperazine is used as a building block in organic synthesis, including the preparation of compounds like acetyl-caffeic acid-1-piperonylpiperazine (HBU-47).
What are the CAS number and formula for 1-Piperonylpiperazine?
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The CAS number for 1-Piperonylpiperazine is 32231-06-4, and its molecular formula is C12H16N2O2.
What grade and purity does Tech Serve Solutions supply for 1-Piperonylpiperazine?
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Tech Serve Solutions supplies 1-Piperonylpiperazine with a minimum assay of 97%. This product is supplied for research and chemical synthesis purposes and is not intended for human or animal consumption, nor is it represented as USP/BP/EP grade.
How should 1-Piperonylpiperazine be handled safely?
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1-Piperonylpiperazine is a Warning substance (GHS07) that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). When handling, wear a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes (P305 + P351 + P338).
Is 1-Piperonylpiperazine a controlled substance?
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The provided data does not indicate that 1-Piperonylpiperazine (CAS: 32231-06-4) is a scheduled or controlled substance. However, users should always verify its regulatory status in their specific jurisdiction.
How is 1-Piperonylpiperazine typically supplied and exported?
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1-Piperonylpiperazine is packaged and prepared according to industry standards for chemical export, ensuring safe transit and compliance with shipping regulations. Contact TSS for specific packaging and shipping details.
How can I request a quote or sample for 1-Piperonylpiperazine?
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To request a quote or sample of 1-Piperonylpiperazine, please use the contact form on the Tech Serve Solutions website or reach out to our sales department directly.
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