1-Piperidinepropionic acid
1-Piperidinepropionic acid (CAS 26371-07-3, C8H15NO2) is a chemical compound with a molecular weight of 157.21 g/mol. It serves as a valuable building block in organic synthesis, particularly for the development of novel pharmaceutical agents. Its utility is demonstrated in the creation of various inhibitors and antagonists, highlighting its importance in medicinal chemistry research and drug discovery programs.
- IUPAC
- 3-Piperidin-1-ylpropionic acid
Synthesis of Protease Activated Receptor 2 Agonists
1-Piperidinepropionic acid is employed as a reactant in the synthesis of compounds designed to activate Protease Activated Receptor 2. This application is relevant in research exploring inflammatory and pain pathways.
Development of Selective 5-HT6 Antagonists
This chemical is utilised in the synthetic routes for selective 5-HT6 receptor antagonists. Such compounds are of interest for their potential in treating cognitive disorders and other neurological conditions.
Inhibitor Synthesis for Kinesin Eg5
1-Piperidinepropionic acid functions as a precursor in the preparation of inhibitors targeting Kinesin Eg5. These inhibitors are investigated for their antiproliferative properties, with potential applications in cancer research.
Ketone Histone Deacetylase Inhibitor Preparation
The compound finds application in the synthesis of selective ketone histone deacetylase inhibitors. These molecules are explored for their role in epigenetic modulation and related therapeutic areas.
JNK2 and JNK3 Inhibitor Development
It is used as a building block in the creation of inhibitors targeting JNK2 and JNK3 kinases, which are implicated in various cellular stress responses and disease states.
Opioid Receptor Antagonist Synthesis
1-Piperidinepropionic acid is a reactant in the synthesis of opioid receptor antagonists, contributing to research in pain management and addiction therapies.
| Molecular weight | 157.21 |
|---|---|
| Empirical formula | C8H15NO2 |
| Assay | 96% |
| Boiling point | 105-108 °C/0.5 mmHg(lit.) |
| Application | Reactant for synthesis of: Protease activated receptor 2 agonists1 Selective 5-HT6 antagonists2 Kinesin Eg5 inhibitors3 Selective ketone histone deacetylase inhibitors4 JNK2 and JNK3 inhibitors5 Opioid receptor antagonists6 |
| Melting point | 105-110 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Piperidinepropionic acid used for?
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1-Piperidinepropionic acid is used as a reactant and building block in organic synthesis, notably for the preparation of protease activated receptor 2 agonists, selective 5-HT6 antagonists, kinesin Eg5 inhibitors, selective ketone histone deacetylase inhibitors, JNK2 and JNK3 inhibitors, and opioid receptor antagonists.
What is the CAS number and formula for 1-Piperidinepropionic acid?
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The CAS number for 1-Piperidinepropionic acid is 26371-07-3, and its empirical formula is C8H15NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Piperidinepropionic acid with a minimum assay of 96%. We do not represent this product as USP, BP, or EP grade.
How should 1-Piperidinepropionic acid be handled safely?
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1-Piperidinepropionic acid is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Ensure adequate ventilation, wear a dust mask (type N95 US recommended), safety eyeshields, and gloves when handling.
Is 1-Piperidinepropionic acid a controlled substance?
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The provided data does not indicate that 1-Piperidinepropionic acid is a controlled substance.
How is 1-Piperidinepropionic acid packed and shipped?
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Tech Serve Solutions can export 1-Piperidinepropionic acid globally. Specific packaging details are available upon request. Please contact us for shipping information.
How can I request a sample or quote for 1-Piperidinepropionic acid?
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To request a sample or a quote for 1-Piperidinepropionic acid, please contact our sales team through our website or by phone. We are happy to assist with your chemical supply needs.
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