1-Methyl-1H-pyrazole-5-boronic acid pinacol ester
1-Methyl-1H-pyrazole-5-boronic acid pinacol ester (CAS: 847818-74-0, C10H17BN2O2) is an organoboron compound with a molecular weight of 208.07 g/mol. This versatile reagent is specifically employed in organic synthesis for the stereoselective preparation of complex amides. Its structure makes it a valuable building block in medicinal chemistry and materials science research, facilitating the construction of novel molecular architectures. TSS supplies this compound with an assay of 97%.
- IUPAC
- 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole,2-(1-Methyl-1H-pyrazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane,2-Methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-pyrazole
- Synonyms
- 2-(1-Methyl-1H-pyrazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Intermediate in Amide Synthesis
This compound serves as a key reagent in the stereoselective synthesis of N-[1-(cyanomethylaminocarbonyl)-2-arylethyl]arylamides. These products are of interest as potential Cathepsin inhibitors.
Heteroaryl Boronate Ester
As a heteroaryl boronate ester, it is a valuable building block in cross-coupling reactions, enabling the introduction of the 1-methyl-1H-pyrazol-5-yl moiety into various organic frameworks.
Research and Development
Utilised in academic and industrial research laboratories for the exploration of new synthetic routes and the development of novel chemical entities for pharmaceutical and material science applications.
| Molecular weight | 208.07 |
|---|---|
| Empirical formula | C10H17BN2O2 |
| Assay | 97% |
| Application | Reagent used for the stereoselective preparation of N-[1-(cyanomethylaminocarbonyl)-2-arylethyl]arylamides used as Cathepsin inhibitors |
| Melting point | 67-71 °C |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester used for?
+
It is used as a reagent in organic synthesis, particularly for the stereoselective preparation of N-[1-(cyanomethylaminocarbonyl)-2-arylethyl]arylamides, which are investigated as Cathepsin inhibitors.
What are the CAS number and molecular formula?
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The CAS number is 847818-74-0 and the molecular formula is C10H17BN2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester with an assay of 97%. This is a research-grade chemical and is not represented as USP, BP, or EP.
How should this chemical be handled?
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This compound is harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H319-H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
Is this chemical supplied internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, including 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester.
How can I get a quote or request a sample?
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Please contact our sales team directly via the website or by phone to request a quote or a sample of 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester.
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