1-Chloro-4-iodobenzene
1-Chloro-4-iodobenzene (CAS: 637-87-6, Formula: ClC6H4I) is a halogenated aromatic compound with a molecular weight of 238.45 g/mol. This chemical serves as a valuable intermediate and building block in organic synthesis, particularly for the introduction of the 4-chlorophenyl group into various molecular structures. Its utility spans across the synthesis of complex organic molecules and research applications.

Organic Synthesis Intermediate
1-Chloro-4-iodobenzene is widely used as a key intermediate in the synthesis of more complex organic compounds. It facilitates the creation of carbon-carbon and carbon-heteroatom bonds through various coupling reactions.
Building Block for Specialty Chemicals
This compound functions as a crucial building block in the development of specialty chemicals, including pharmaceuticals and agrochemicals. Its structure allows for regioselective functionalization.
Research and Development
In research laboratories, 1-Chloro-4-iodobenzene is employed in the development of novel synthetic methodologies and the exploration of new chemical entities. Its reactivity makes it a versatile reagent for academic and industrial R&D.
| Molecular weight | 238.45 |
|---|---|
| Linear formula | ClC6H4I |
| Assay | 99% |
| Boiling point | 226-227 °C(lit.) |
| Melting point | 53-54 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 108 °C / 226.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Chloro-4-iodobenzene used for?
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1-Chloro-4-iodobenzene is primarily used as an intermediate and building block in organic synthesis, including the development of pharmaceuticals and specialty chemicals, as well as in research and development applications.
What are the CAS number and formula for 1-Chloro-4-iodobenzene?
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The CAS number for 1-Chloro-4-iodobenzene is 637-87-6, and its chemical formula is ClC6H4I.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Chloro-4-iodobenzene with an assay of 99%. This product is intended for laboratory and research use; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 1-Chloro-4-iodobenzene be handled safely?
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1-Chloro-4-iodobenzene is harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Handle with appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Work in a well-ventilated area.
Is 1-Chloro-4-iodobenzene a controlled substance?
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The provided data does not indicate that 1-Chloro-4-iodobenzene is a controlled substance.
How is 1-Chloro-4-iodobenzene packed and shipped?
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1-Chloro-4-iodobenzene is carefully packed and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical products.
How can I request a quote or sample for 1-Chloro-4-iodobenzene?
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To request a quote or sample for 1-Chloro-4-iodobenzene, please contact our sales team through the website or by phone, providing your specific requirements.
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