1-Bromo-2-methylpropane
1-Bromo-2-methylpropane (CAS: 78-77-3) is a halogenated hydrocarbon with the molecular formula (CH3)2CHCH2Br and a molecular weight of 137.02 g/mol. This organic building block is primarily utilised in chemical synthesis. It serves as a versatile intermediate, offering a reactive bromine atom for various organic transformations. Tech Serve Solutions supplies this compound for research and industrial applications requiring precise chemical building blocks.
- IUPAC
- Isobutyl bromide

Organic Synthesis Intermediate
1-Bromo-2-methylpropane functions as a key alkylating agent in organic synthesis. Its reactivity allows for the introduction of the isobutyl group into various molecular structures.
Precursor for Heterocyclic Compounds
This compound has been employed in the synthesis of heterocyclic structures, such as imidazolium salts. For instance, it reacts with imidazole derivatives to form functionalised ionic liquids.
Building Block in Pharmaceutical Research
As a readily available organic building block, 1-Bromo-2-methylpropane can be used in the development of novel pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
| Molecular weight | 137.02 |
|---|---|
| Linear formula | (CH3)2CHCH2Br |
| Assay | ≥97.0% (GC) |
| Boiling point | 90-92 °C(lit.) |
| Density | 1.26 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.435(lit.)n20/D 1.436 |
| Application | Isobutyl bromide has been used in a reaction with 1-ethylimidazole in a 140 °C oil bath to yield 97% 1-ethyl-1,3-isobutylimidazolium bromide.1 |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 18 °C / 64.4 °F |
| Transport (UN / ADR) | UN 2342 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xi |
| Risk statements (R) | 11-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2-methylpropane used for?
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1-Bromo-2-methylpropane is used as an intermediate in organic synthesis and as a building block for creating more complex molecules, including heterocyclic compounds and potential pharmaceutical intermediates.
What is the CAS number and formula for 1-Bromo-2-methylpropane?
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The CAS number for 1-Bromo-2-methylpropane is 78-77-3, and its linear formula is (CH3)2CHCH2Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-2-methylpropane with an assay of ≥97.0% (GC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
What are the primary safety hazards associated with 1-Bromo-2-methylpropane?
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1-Bromo-2-methylpropane is classified as highly flammable (H225) and can cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used when handling.
How is 1-Bromo-2-methylpropane packed, shipped, and exported?
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1-Bromo-2-methylpropane is carefully packed according to international shipping regulations for hazardous materials, including UN 2342, Class 3, Packing Group II. Tech Serve Solutions handles global export of this chemical.
How can I request a sample or a quote for 1-Bromo-2-methylpropane?
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To request a sample or a quote for 1-Bromo-2-methylpropane, please contact our sales team through the website or by phone, providing your specific requirements.
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