1-Bromo-2-nitrobenzene
1-Bromo-2-nitrobenzene (CAS: 577-19-5; Formula: BrC6H4NO2; Molar Mass: 202.01 g/mol) is a valuable organic compound recognised for its utility as a chemical intermediate. It serves as a key building block in the synthesis of more complex molecules within the pharmaceutical and chemical industries. Its distinctive structure, featuring both a bromine atom and a nitro group on a benzene ring, facilitates diverse chemical transformations for advanced organic synthesis.
Pharmaceutical Intermediate Synthesis
1-Bromo-2-nitrobenzene is employed as a precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its functional groups allow for targeted modifications to build complex molecular architectures required for drug development.
Organic Synthesis Building Block
This compound serves as a versatile building block in general organic synthesis. It is used to introduce the 2-nitrophenyl bromide moiety into target molecules, enabling the creation of novel compounds for research and development.
Research and Development
Used in academic and industrial research settings, 1-Bromo-2-nitrobenzene facilitates the exploration of new chemical reactions and the development of innovative materials. Its reactivity makes it a useful tool for synthetic chemists.
| Molecular weight | 202.01 |
|---|---|
| Linear formula | BrC6H4NO2 |
| Assay | 98% |
| Boiling point | 261 °C(lit.) |
| Storage temperature | 2-8°C |
| Melting point | 40-42 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 112 °C / 233.6 °F |
| Transport (UN / ADR) | UN 3459 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2-nitrobenzene typically used for?
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1-Bromo-2-nitrobenzene is primarily used as a building block in chemical synthesis, particularly for pharmaceutical intermediates and in organic chemistry research.
What is the CAS number and molecular formula for 1-Bromo-2-nitrobenzene?
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The CAS number is 577-19-5, and the molecular formula is BrC6H4NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-2-nitrobenzene with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 1-Bromo-2-nitrobenzene be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. It is classified as harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332).
How is 1-Bromo-2-nitrobenzene packed and exported?
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1-Bromo-2-nitrobenzene is packed according to international shipping regulations, including UN 3459 classification for hazardous materials, and exported globally by Tech Serve Solutions.
How can I request a quote or sample for 1-Bromo-2-nitrobenzene?
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To request a quote or sample, please contact our sales team through the website or via email, providing your specific requirements.
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