1-Bromo-2,3,5-trifluorobenzene
1-Bromo-2,3,5-trifluorobenzene (CAS: 133739-70-5), with the molecular formula BrC6H2F3 and a molecular weight of 210.98 g/mol, is a halogenated aromatic compound. It serves as a versatile building block in organic synthesis. This compound is characterised by its unique substitution pattern of bromine and fluorine atoms on the benzene ring, making it valuable for introducing fluorinated aromatic moieties into more complex molecules for various chemical research and development applications.
- Synonyms
- 133739-70-5BrC6H2F3

Organic Synthesis Intermediate
1-Bromo-2,3,5-trifluorobenzene acts as a key intermediate in the synthesis of diverse organic compounds. Its reactive bromine atom allows for facile functionalization through cross-coupling reactions and other transformations.
Fluorinated Aromatic Building Block
This compound is utilised as a building block for constructing fluorinated aromatic systems. These motifs are of interest in the development of pharmaceuticals, agrochemicals, and advanced materials due to the unique electronic and lipophilic properties conferred by fluorine.
Research and Development
It is employed in research laboratories for the exploration of new synthetic pathways and the creation of novel molecules with tailored properties. Its specific substitution pattern offers opportunities for regioselective synthesis.
| Molecular weight | 210.98 |
|---|---|
| Linear formula | BrC6H2F3 |
| Assay | 98% |
| Density | 1.758 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.486(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 32 °C / 89.6 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Bromo-2,3,5-trifluorobenzene used for?
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1-Bromo-2,3,5-trifluorobenzene is primarily used as a versatile intermediate and building block in organic synthesis, particularly for introducing fluorinated aromatic moieties into complex molecules for research and development in areas like pharmaceuticals and materials science.
What are the CAS number and formula for 1-Bromo-2,3,5-trifluorobenzene?
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The CAS number is 133739-70-5, and the linear formula is BrC6H2F3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Bromo-2,3,5-trifluorobenzene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 1-Bromo-2,3,5-trifluorobenzene be handled safely?
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1-Bromo-2,3,5-trifluorobenzene is a flammable liquid and vapour (H226) and causes skin (H315), eye (H319), and respiratory irritation (H335). Handle in a well-ventilated area, away from ignition sources, using appropriate personal protective equipment including eyeshields, gloves, and respiratory protection (e.g., type ABEK respirator filter).
Is this chemical controlled or scheduled?
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The provided data does not indicate that 1-Bromo-2,3,5-trifluorobenzene is a controlled or scheduled substance.
How is 1-Bromo-2,3,5-trifluorobenzene packed, shipped, and exported?
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1-Bromo-2,3,5-trifluorobenzene is packed according to safety regulations for flammable liquids and is exported globally by Tech Serve Solutions, adhering to all international shipping requirements.
How can I request a sample or quote for 1-Bromo-2,3,5-trifluorobenzene?
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Please contact our sales team via the website or direct email to request a sample or a quotation for 1-Bromo-2,3,5-trifluorobenzene.
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