1-Boc-3-hydroxypiperidine
1-Boc-3-hydroxypiperidine (CAS: 85275-45-2), with the molecular formula C10H19NO3 and a molecular weight of 201.26 g/mol, is a valuable chiral building block. This piperidine derivative features a Boc-protected amine and a hydroxyl group, making it a versatile intermediate in asymmetric synthesis and heterocyclic chemistry. It serves as a key component in the construction of complex organic molecules, particularly within pharmaceutical research and development.
- IUPAC
- 1-Boc-3-piperidinol,tert-Butyl 3-hydroxy-1-piperidinecarboxylate
- Synonyms
- tert-Butyl 3-hydroxy-1-piperidinecarboxylate
Asymmetric Synthesis
1-Boc-3-hydroxypiperidine is utilised as a chiral precursor in enantioselective synthesis. Its defined stereochemistry allows for the controlled introduction of chirality into target molecules.
Pharmaceutical Intermediates
This compound serves as a key building block in the synthesis of various pharmaceutical agents. The piperidine ring is a common motif in many biologically active compounds.
Heterocyclic Chemistry
As a functionalised heterocyclic compound, it is employed in the construction and modification of diverse ring systems within organic synthesis.
Organic Synthesis Reagent
It acts as a versatile reagent for introducing the protected 3-hydroxypiperidine moiety into more complex molecular structures.
| Molecular weight | 201.26 |
|---|---|
| Empirical formula | C10H19NO3 |
| Assay | ≥98.0% (TLC) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-3-hydroxypiperidine used for?
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1-Boc-3-hydroxypiperidine is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in the production of pharmaceutical agents and other complex organic molecules.
What are the CAS number and formula for 1-Boc-3-hydroxypiperidine?
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The CAS number for 1-Boc-3-hydroxypiperidine is 85275-45-2, and its empirical formula is C10H19NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-3-hydroxypiperidine with an assay of ≥98.0% (TLC). This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, or EP grade.
How should 1-Boc-3-hydroxypiperidine be handled safely?
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1-Boc-3-hydroxypiperidine is classified as a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves, should be used. Ensure good ventilation. In case of contact, rinse cautiously with water for several minutes and seek medical advice if irritation persists. Refer to the safety data sheet for full handling instructions.
Is 1-Boc-3-hydroxypiperidine a controlled substance?
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Based on the provided data, there is no indication that 1-Boc-3-hydroxypiperidine is a controlled substance.
How is 1-Boc-3-hydroxypiperidine packed and shipped?
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1-Boc-3-hydroxypiperidine is available from Tech Serve Solutions, a global supplier and exporter. Specific packing and shipping details are confirmed upon order.
How can I request a sample or quote for 1-Boc-3-hydroxypiperidine?
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To request a sample or a quote for 1-Boc-3-hydroxypiperidine, please contact the Tech Serve Solutions sales team through our website or direct contact information.
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