1-Boc-3-hydroxyazetidine
1-Boc-3-hydroxyazetidine (CAS: 141699-55-0, C8H15NO3) is a valuable heterocyclic building block with a molecular weight of 173.21 g/mol. This compound, featuring a protected hydroxyl group on an azetidine ring, serves as a key intermediate in complex organic synthesis. Its structure makes it particularly useful in the development of novel pharmaceutical agents and advanced materials where precise molecular architecture is critical.
- IUPAC
- tert-Butyl 3-hydroxyazetidine-1-carboxylate

Pharmaceutical Intermediate
1-Boc-3-hydroxyazetidine is widely employed in the synthesis of active pharmaceutical ingredients (APIs). Its azetidine core can be incorporated into drug candidates targeting various therapeutic areas, contributing to molecular diversity and improved pharmacokinetic properties.
Agrochemical Synthesis
The unique structural features of this compound make it a useful building block in the development of novel agrochemicals. It can be utilized to create new pesticides, herbicides, and fungicides with enhanced efficacy and targeted action.
Materials Science
This azetidine derivative can be incorporated into polymers and advanced materials. Its inclusion can impart specific chemical or physical properties, leading to the development of novel functional materials for specialized applications.
Organic Synthesis Reagent
As a versatile building block, 1-Boc-3-hydroxyazetidine facilitates the construction of complex organic molecules. It is frequently used in academic and industrial research laboratories for exploring new synthetic routes and methodologies.
| Molecular weight | 173.21 |
|---|---|
| Empirical formula | C8H15NO3 |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Melting point | 36-43 °C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-3-hydroxyazetidine used for?
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1-Boc-3-hydroxyazetidine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials. It serves as a key intermediate for introducing the azetidine moiety into larger, more complex molecules.
What is the CAS number and chemical formula for 1-Boc-3-hydroxyazetidine?
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The CAS number for 1-Boc-3-hydroxyazetidine is 141699-55-0, and its empirical formula (Hill notation) is C8H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-3-hydroxyazetidine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 1-Boc-3-hydroxyazetidine be handled and stored?
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1-Boc-3-hydroxyazetidine is classified as Dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C. Refer to the Safety Data Sheet for detailed handling procedures.
Is 1-Boc-3-hydroxyazetidine a controlled substance?
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The provided data does not indicate that 1-Boc-3-hydroxyazetidine is a controlled substance.
How is 1-Boc-3-hydroxyazetidine packed and exported?
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1-Boc-3-hydroxyazetidine is carefully packed to maintain its integrity during transit and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a quote or sample?
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To request a quote or a sample of 1-Boc-3-hydroxyazetidine, please contact our sales department through the TSS website or designated sales channels.
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