(−)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol

CAS 37002-45-2C21H26O8S2Chemical Synthesis

(−)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol (CAS 37002-45-2) is a carbohydrate derivative with the molecular formula C21H26O8S2 and a molecular weight of 470.56. This compound is a valuable building block in organic synthesis, particularly in carbohydrate chemistry. Its tosylate groups provide excellent leaving characteristics, enabling diverse synthetic transformations and the introduction of various functional groups. It is primarily employed in advanced chemical synthesis and research applications.

IUPAC: (−)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol,(−)-2,3-O-Isopropylidene-L-threitol 1,4-ditosylate,(4S,5S)-4,5-Bis(tosyloxymethyl)-2,2-dimethyl-1,3-dioxolane
Synonyms: (−)-2,3-O-Isopropylidene-1,4-di-O-tosyl-L-threitol(−)-2,3-O-Isopropylidene-L-threitol 1,4-ditosylate(4S,5S)-4,5-Bis(tosyloxymethyl)-2,2-dimethyl-1,3-dioxolane

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(−)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol (C21H26O8S2) — chemical structure, CAS 37002-45-2; Chemistry, fine chemical supplied by Tech Serve Solutions

Carbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical Synthesis

01 /Applications

Chiral Synthesis Intermediate

Utilised as a precursor in the stereoselective synthesis of complex molecules, leveraging its inherent chirality derived from L-threitol.

Carbohydrate Derivative Modification

Serves as a versatile intermediate for derivatising carbohydrate structures, enabling the creation of novel compounds with tailored properties for research.

Research and Development

Employed in academic and industrial research settings for exploring new synthetic pathways and developing novel chemical entities.

02 /Properties

Molecular weight	470.56
Empirical formula	C21H26O8S2
Assay	≥98.0% (C/S)
Grade	purum
Optical activity	[α]20/D −13±1°, c = 8.8% in chloroform
Melting point	90-92 °C(lit.)90-92 °C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

37002-45-2

MDL number

MFCD00003212

PubChem substance

24867470

Beilstein registry

99610

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-1,4-Di-O-tosyl-2,3-O-isopropylidene-L-threitol used for?

This compound is primarily used as an intermediate in organic synthesis, particularly within carbohydrate chemistry and chiral synthesis, for the development of complex molecules and novel chemical entities.

What is the CAS number and formula for this compound?

The CAS number is 37002-45-2, and the empirical formula (Hill notation) is C21H26O8S2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this compound with a grade of 'purum' and an assay of ≥98.0% (C/S). It is not supplied as USP, BP, or EP grade.

What are the safety and handling considerations for this chemical?

This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It is classified under WGK Germany 3, indicating a high hazard to water.

Is this compound controlled or scheduled?

There is no indication in the provided data that this compound is controlled or scheduled.

How is this chemical typically packed and exported?

Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents, ensuring appropriate packaging and adherence to international shipping regulations for export.