1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 6289-04-9; molecular formula C11H8ClN5; molar mass 245.67 g/mol) is a fused bicyclic heterocyclic building block. It pairs a 4-aminopyrazolo[3,4-d]pyrimidine core, a recognised purine (adenine) bioisostere, with an N1-(4-chlorophenyl) group. Supplied as a research-grade solid, it is used principally in medicinal-chemistry and chemical-synthesis programmes as an intermediate and scaffold for further functionalisation. Tech Serve Solutions supplies and exports this reagent worldwide.
- Synonyms
- 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine1-(4-Chlorophenyl)pyrazolo[3,4-d]pyrimidin-4-amine4-Amino-1-(4-chlorophenyl)pyrazolo[3,4-d]pyrimidine1-(4-Chlorophenyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidineCAS 6289-04-9
![1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (C11H8ClN5) — chemical structure, CAS 6289-04-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F6289-04-9.png&w=3840&q=75)
Pharmaceutical and medicinal-chemistry intermediate
Serves as a heterocyclic intermediate in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives. The free 4-amino group and N1-aryl substitution provide handles for onward derivatisation in discovery chemistry.
Purine-bioisostere scaffold
The pyrazolo[3,4-d]pyrimidin-4-amine core is a well-documented adenine mimic, making this compound a useful template in structure-activity studies that explore purine-recognising biological targets.
Heterocyclic building block for synthesis
Used as a halogenated heterocyclic building block in chemical synthesis, where the aryl chloride and fused ring system support cross-coupling, substitution and library-generation strategies.
Reference and research reagent
Suitable as a characterised reagent for laboratory research, method development and analytical reference work where a defined pyrazolopyrimidine standard is required.
| Molecular weight | 245.67 |
|---|---|
| Empirical formula | C11H8ClN5 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine used for?
+
It is used mainly as a research and medicinal-chemistry building block. The 4-aminopyrazolo[3,4-d]pyrimidine scaffold is a purine (adenine) bioisostere, so the compound serves as an intermediate and template for synthesising and studying pyrazolo[3,4-d]pyrimidine derivatives. We supply it for research and manufacturing use, not for clinical or consumer use.
What is the CAS number and molecular formula of 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine?
+
The CAS number is 6289-04-9. The molecular formula is C11H8ClN5 (Hill notation), with a molecular weight of 245.67 g/mol.
What grade and purity does Tech Serve Solutions supply?
+
We supply this compound as a research / technical grade reagent and characterise each batch on request, with a Certificate of Analysis and SDS provided. No pharmacopoeial claim is made: we do not represent it as USP, BP or EP grade. If you have a specific assay or specification requirement, share it with your enquiry and we will confirm availability.
How should 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine be handled and stored?
+
Handle as a research chemical using good laboratory practice: work in a fume hood, wear suitable gloves, eye protection and a lab coat, and avoid raising or inhaling dust. Store in a tightly closed container in a cool, dry, well-ventilated place away from incompatible materials. A formal hazard classification was not supplied with this listing, so always review the current Safety Data Sheet, which accompanies every shipment, before use.
How is 1-(4-Chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine packed, shipped and exported?
+
The material is packed as a solid in appropriately sealed, labelled containers, from gram research quantities to larger volumes, with packaging selected to protect product integrity in transit. Tech Serve Solutions exports worldwide and arranges documentation, the relevant SDS and compliant transport in line with destination and carrier requirements.
How do I request a sample or quote?
+
Send an enquiry to Tech Serve Solutions stating the quantity, your required specification and the destination country. We will respond with availability, lead time, documentation and a quotation, and can arrange a sample where appropriate.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis