1,4-Bis(trifluoromethyl)benzene
1,4-Bis(trifluoromethyl)benzene (CAS 433-19-2), with the linear formula C6H4(CF3)2 and a molecular weight of 214.11 g/mol, is a fluorinated aromatic compound. It serves as a valuable building block in organic synthesis. Its properties make it suitable for applications in the development of advanced materials and complex organic molecules within research and industrial settings.
- IUPAC
- α,α,α,α′,α′,α′-Hexafluoro-p-xylene
- Synonyms
- α,α,α,α′,α′,α′-Hexafluoro-p-xylene

Organic Synthesis Building Block
This compound is a key intermediate for introducing the 1,4-bis(trifluoromethyl)phenyl moiety into larger molecules. Its structure is useful in the synthesis of various organic compounds, including potential pharmaceuticals and agrochemicals.
Material Science Research
The electron-withdrawing nature of the trifluoromethyl groups can influence the electronic and physical properties of polymers and other materials. This makes it a candidate for research in advanced materials development.
Fluorinated Compound Synthesis
It acts as a precursor for creating more complex fluorinated organic molecules. Research into fluorinated compounds is vital for developing novel substances with unique properties for diverse applications.
| Molecular weight | 214.11 |
|---|---|
| Linear formula | C6H4(CF3)2 |
| Assay | 98% |
| Boiling point | 116 °C(lit.) |
| Density | 1.381 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.379(lit.) |


Hazard statements
- H225Highly flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 22 °C / 71.6 °F |
| Transport (UN / ADR) | UN 1993BF 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 16-26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,4-Bis(trifluoromethyl)benzene used for?
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1,4-Bis(trifluoromethyl)benzene is primarily used as a building block in organic synthesis and for research in material science, particularly in the development of new fluorinated organic compounds.
What is the CAS number and formula for 1,4-Bis(trifluoromethyl)benzene?
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The CAS number is 433-19-2 and the linear formula is C6H4(CF3)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,4-Bis(trifluoromethyl)benzene with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 1,4-Bis(trifluoromethyl)benzene be handled?
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1,4-Bis(trifluoromethyl)benzene is a flammable liquid and vapour, and can cause skin, serious eye, and respiratory irritation. Handle with appropriate personal protective equipment including eyeshields, faceshields, and suitable gloves. Ensure good ventilation and keep away from heat, sparks, and open flames.
Is 1,4-Bis(trifluoromethyl)benzene a controlled substance?
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The provided data does not indicate that 1,4-Bis(trifluoromethyl)benzene is a controlled substance.
How is 1,4-Bis(trifluoromethyl)benzene packed and shipped?
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This chemical is shipped as a flammable liquid, UN 1993, Packing Group II. Specific packaging details can be confirmed upon request.
How can I request a quote or sample of 1,4-Bis(trifluoromethyl)benzene?
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To request a quote or sample, please contact our sales department through our website or by phone, providing your specific requirements and shipping details.
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