1,3-Bis(trifluoromethyl)benzene
1,3-Bis(trifluoromethyl)benzene (CAS: 402-31-3) is a halogenated aromatic hydrocarbon with the molecular formula C₆H₄(CF₃)₂. It serves as a valuable building block in organic synthesis, particularly in the creation of complex molecules for the pharmaceutical and agrochemical industries. Its unique trifluoromethyl groups impart specific electronic and lipophilic properties, making it a sought-after intermediate for advanced chemical research and development.
- IUPAC
- α,α,α,α′,α′,α′-Hexafluoro-m-xylene
- Synonyms
- α,α,α,α′,α′,α′-Hexafluoro-m-xyleneC6H4(CF3)2
Organic Synthesis Intermediate
1,3-Bis(trifluoromethyl)benzene is extensively used as a key intermediate in the synthesis of various organic compounds. Its structure allows for further functionalization, enabling the development of novel molecules with tailored properties for diverse applications.
Pharmaceutical Research
This compound is employed in the research and development of new pharmaceutical agents. The trifluoromethyl groups can enhance the metabolic stability and bioavailability of drug candidates, making it a valuable component in medicinal chemistry.
Agrochemical Development
It finds application in the synthesis of agrochemicals, contributing to the development of new pesticides and herbicides. The presence of fluorine atoms can influence the biological activity and environmental persistence of these compounds.
Material Science
1,3-Bis(trifluoromethyl)benzene can be used in the development of advanced materials. Its fluorinated structure may impart unique thermal, chemical, and electrical properties to polymers and other materials.
| Molecular weight | 214.11 |
|---|---|
| Linear formula | C6H4(CF3)2 |
| Assay | 99% |
| Boiling point | 116-116.3 °C(lit.) |
| Density | 1.378 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.379(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 1993C 3 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 10-36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1,3-Bis(trifluoromethyl)benzene used for?
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1,3-Bis(trifluoromethyl)benzene is primarily used as a building block in organic synthesis, particularly for pharmaceutical research, agrochemical development, and in the creation of advanced materials.
What is the CAS number and formula for 1,3-Bis(trifluoromethyl)benzene?
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The CAS number for 1,3-Bis(trifluoromethyl)benzene is 402-31-3, and its molecular formula is C₆H₄(CF₃)₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1,3-Bis(trifluoromethyl)benzene with a minimum assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 1,3-Bis(trifluoromethyl)benzene be handled safely?
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1,3-Bis(trifluoromethyl)benzene is a flammable liquid and vapour (H226) and can cause skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Handle with appropriate personal protective equipment, including eyeshields, face shields, and chemical-resistant gloves, in a well-ventilated area. Avoid sources of ignition.
Is 1,3-Bis(trifluoromethyl)benzene a controlled substance?
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The provided data does not indicate that 1,3-Bis(trifluoromethyl)benzene is a controlled substance.
How is 1,3-Bis(trifluoromethyl)benzene packed, shipped, or exported?
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1,3-Bis(trifluoromethyl)benzene is shipped as a flammable liquid, UN 1993, Packing Group III. TSS adheres to all international regulations for the safe transport of chemicals.
How can I request a sample or quote for 1,3-Bis(trifluoromethyl)benzene?
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Please contact our sales team directly through our website or by phone to request a sample or a quotation for 1,3-Bis(trifluoromethyl)benzene.
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