Phenolphthalein β-D-glucuronide
Phenolphthalein β-D-glucuronide (CAS: 15265-26-6; Formula: C26H22O10) is a biochemical reagent with a molecular weight of 494.45 g/mol. It serves as a chromogenic substrate specifically for the detection and quantification of β-glucuronidase activity. This compound is instrumental in various diagnostic and research applications, particularly for studying liver and bacterial enzymes involved in glucuronidation pathways.
- IUPAC
- Phenolphthalein β-D-glucosiduronic acid,Phenolphthalein glucuronic acid,Phenolphthalein mono-β-D-glucosiduronic acid,Phenolphthalein-mono-β-glucuronic acid from rabbit urine
β-Glucuronidase Enzyme Assays
Phenolphthalein β-D-glucuronide is employed as a substrate in assays designed to measure the activity of β-glucuronidase enzymes. Upon enzymatic cleavage, it releases phenolphthalein, which can be detected spectrophotometrically, enabling quantitative analysis.
Detection of Bacterial Enzymes
This substrate is suitable for identifying and quantifying bacterial β-glucuronidase, an enzyme often associated with the presence of certain microorganisms, including specific strains of E. coli.
Liver Enzyme Studies
The compound can be utilised in research settings to investigate the activity of β-glucuronidase in liver tissues, playing a role in understanding drug metabolism and detoxification processes.
| Molecular weight | 494.45 |
|---|---|
| Empirical formula | C26H22O10 |
| Solubility | H2O: soluble100 mg/mL |
| Application | β-glucuronidase test: suitable as substrate, for liver and bacterial enzymes |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Phenolphthalein β-D-glucuronide used for?
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Phenolphthalein β-D-glucuronide is used as a chromogenic substrate for the assay of β-glucuronidase activity, suitable for liver and bacterial enzymes.
What is the CAS number and formula for Phenolphthalein β-D-glucuronide?
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The CAS number is 15265-26-6 and the empirical formula (Hill notation) is C26H22O10.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product as a research chemical. Purity details are available on the specification sheet. It is not supplied as USP, BP, EP, or pharmaceutical grade.
How should Phenolphthalein β-D-glucuronide be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK Germany rating of 3, indicating it is hazardous to water.
Is Phenolphthalein β-D-glucuronide a controlled substance?
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Based on the provided data, Phenolphthalein β-D-glucuronide is not listed as a controlled substance.
How is Phenolphthalein β-D-glucuronide packed and exported?
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Tech Serve Solutions securely packs and exports chemicals globally, adhering to all relevant shipping regulations for research reagents.
How can I request a quote or sample for Phenolphthalein β-D-glucuronide?
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Please contact our sales department or use the online enquiry form to request a quote or sample for Phenolphthalein β-D-glucuronide.
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