Neocuproine hydrate
Neocuproine hydrate (CAS 654054-57-6), with the formula C14H12N2 · xH2O, is a specialized organic compound. It is known for its utility as a building block in chemical synthesis, particularly within heterocyclic chemistry. This hydrate form is primarily recognized for its application in analytical chemistry, notably for the determination of copper ions using electrochemiluminescence. Its anhydrous molecular weight is 208.26.
- IUPAC
- 2,9-Dimethyl-1,10-phenanthroline hydrate

Analytical Reagent for Copper Determination
Neocuproine hydrate is employed in the precise determination of copper ions within aqueous solutions. Its effectiveness is demonstrated in electrochemiluminescence-based analytical methods, providing a sensitive approach for copper quantification.
Heterocyclic Building Block
As a heterocyclic building block, Neocuproine hydrate serves as a valuable intermediate in organic synthesis. It facilitates the construction of complex molecules within the realm of N-containing heterocycles for various chemical research and development endeavours.
Chemical Synthesis Intermediate
This compound functions as a key component in synthetic organic chemistry. Researchers and chemists utilise Neocuproine hydrate to introduce specific structural motifs and functional groups into target molecules.
| Molecular weight | 208.26 (anhydrous basis) |
|---|---|
| Empirical formula | C14H12N2 · xH2O |
| Assay | 99% |
| Solubility | methanol: soluble50 mg/mL, clear, colorless to dark yellow |
| Application | Neocuproine hydrate was used in determination of copper ions in aqueous solution using electrochemiluminescence1. |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Neocuproine hydrate primarily used for?
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Neocuproine hydrate is used as a reagent for the determination of copper ions in aqueous solutions via electrochemiluminescence and as a heterocyclic building block in chemical synthesis.
What are the CAS number and formula for Neocuproine hydrate?
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The CAS number is 654054-57-6, and the empirical formula is C14H12N2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Neocuproine hydrate with an assay of 99%. We do not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should Neocuproine hydrate be handled safely?
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Neocuproine hydrate is a warning substance that may cause skin irritation (H315), eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves. Ensure adequate ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes (P305 + P351 + P338).
Can Tech Serve Solutions export Neocuproine hydrate?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for Neocuproine hydrate?
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Please contact our sales team through the website or by phone to request a sample or a quotation for Neocuproine hydrate.
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