N,N′-Dicyclohexyl-4-morpholinecarboxamidine
N,N′-Dicyclohexyl-4-morpholinecarboxamidine (CAS 4975-73-9; C17H31N3O; molar mass 293.45 g/mol) is a morpholine-based amidine supplied as a research-grade building block. A crystalline solid melting at 105–107 °C, this sterically hindered guanidine-type reagent is valued in organic and medicinal chemistry, notably for preparing alkoxyalkyl analogues of nucleotide phosphonates such as cidofovir and cyclic cidofovir. Tech Serve Solutions supplies it worldwide at 98% assay to laboratory and synthesis customers.
- Synonyms
- N,N′-Dicyclohexyl-4-morpholinecarboxamidineN,N'-Dicyclohexyl-4-morpholinecarboxamidine4-Morpholinecarboxamidine, N,N′-dicyclohexyl-N,N′-Dicyclohexylmorpholine-4-carboxamidineDCMCC17H31N3O
Coupling reagent for nucleotide phosphonates
Documented as a reagent in the synthesis of alkoxyalkyl analogues of nucleotide phosphonates, including cidofovir and cyclic cidofovir. The hindered amidine assists esterification and condensation steps in phosphonate chemistry.
Heterocyclic building block
Serves as a morpholine-containing C11–C20+ building block for chemical synthesis, providing an amidine functionality for constructing more elaborate nitrogen-rich molecules.
Medicinal chemistry intermediate
Used in discovery-scale routes where an amidine base and a morpholine ring are required, supporting the preparation of pharmaceutical intermediates and analogue libraries.
Laboratory reagent
Employed as a general organic-synthesis reagent in research settings, where its defined assay and known melting point aid reproducible bench-scale work.
| Molecular weight | 293.45 |
|---|---|
| Empirical formula | C17H31N3O |
| Assay | 98% |
| Application | N,N′-Dicyclohexyl-4-morpholinecarboxamidine was used as reagent in the synthesis of alkoxyalkyl analogs of nucleotide phosphonates, cidofovir and cyclic cidofovir1. |
| Melting point | 105-107 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N,N′-Dicyclohexyl-4-morpholinecarboxamidine used for?
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It is used as a specialty reagent and heterocyclic building block in organic and medicinal chemistry. It is documented in the synthesis of alkoxyalkyl analogues of nucleotide phosphonates, including cidofovir and cyclic cidofovir, and serves more generally as a morpholine-based amidine intermediate.
What is the CAS number and molecular formula of N,N′-Dicyclohexyl-4-morpholinecarboxamidine?
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Its CAS number is 4975-73-9 and its empirical formula is C17H31N3O (Hill notation), with a molecular weight of 293.45 g/mol. The MDL number is MFCD00063252 and the EC number is 225-622-1.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a typical assay of 98% as a research/technical-grade reagent. We do not represent it as USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each batch, and the reported melting point is 105–107 °C.
What are the safety and handling requirements?
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The material is classified GHS07 with signal word Warning. Hazard statements are H315 (causes skin irritation), H319 (causes serious eye irritation) and H335 (may cause respiratory irritation). Follow precautionary advice P261 and P305+P351+P338: avoid breathing dust, wear suitable gloves and eye protection, and on eye contact rinse cautiously with water. It carries WGK Germany water-hazard class 3, so prevent release to drains and watercourses. Always consult the SDS before use.
How is N,N′-Dicyclohexyl-4-morpholinecarboxamidine packed, shipped and exported?
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It is packed in sealed laboratory and bulk containers appropriate to the order quantity, with full labelling and documentation. Tech Serve Solutions exports globally, supplying a certificate of analysis and safety data sheet, and arranges compliant transport in line with the applicable regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, assay and destination, and our team will respond with availability, lead time and documentation. Samples can be arranged for qualification subject to availability.
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