N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 898561-68-7; C11H16N2O2; molar mass 208.26 g/mol) is a heterocyclic building block in which a 5-methoxypyridin-2-amine carries a pivaloyl (2,2-dimethylpropanamide) group on nitrogen. The bulky pivalamide serves as a directing and protecting group on the aminopyridine scaffold, making the compound a useful intermediate in chemical synthesis and medicinal-chemistry research. Tech Serve Solutions supplies it for laboratory and process applications.
- Synonyms
- N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamideN-(5-Methoxypyridin-2-yl)pivalamideN-(5-Methoxy-2-pyridinyl)-2,2-dimethylpropanamide2,2-Dimethyl-N-(5-methoxypyridin-2-yl)propanamideCAS 898561-68-7
Pyridine building block for synthesis
Functions as a substituted aminopyridine intermediate for constructing more elaborate heterocyclic scaffolds. The pre-installed 5-methoxy substituent and 2-amino position provide defined handles for further functionalisation.
Protected aminopyridine
The 2,2-dimethylpropanamide (pivalamide) acts as a robust protecting group for the 2-amino function, allowing selective reactions elsewhere on the ring before the amine is unmasked.
Directed metalation and C-H functionalisation
Pivalamido groups on aromatic and heteroaromatic rings are widely used as directing groups for ortho-metalation and transition-metal-catalysed C-H functionalisation, supporting regioselective derivatisation of the pyridine core.
Medicinal and discovery chemistry
Serves as a research intermediate in medicinal-chemistry programmes that build on methoxy-substituted pyridine cores. Specific downstream targets depend on the synthetic route chosen by the user.
| Molecular weight | 208.26 |
|---|---|
| Empirical formula | C11H16N2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used principally as a heterocyclic building block and synthetic intermediate. The molecule is a pivaloyl-protected 5-methoxypyridin-2-amine, and the pivalamide group commonly acts as both a protecting group for the amine and a directing group for regioselective functionalisation of the pyridine ring in chemical synthesis and medicinal-chemistry research.
What is the CAS number and molecular formula of N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 898561-68-7. The empirical formula is C11H16N2O2 (Hill notation), corresponding to a molecular weight of 208.26 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply this compound as a research and laboratory-grade building block for synthetic and research use. A specific assay value is not stated here; please request the current specification or certificate of analysis for a given lot. We do not represent the material as USP, BP or EP pharmacopoeial grade.
How should N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide be handled and stored?
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No GHS classification data is provided in our current record for this item, so it should not be assumed to be non-hazardous. Handle it as a research chemical using good laboratory practice, wearing suitable gloves, eye protection and a lab coat, working with adequate ventilation, and storing the container tightly closed in a cool, dry place. Always consult the Safety Data Sheet supplied with the product before use.
How is N-(5-Methoxy-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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The compound is packed in appropriately sealed, labelled containers sized to the order, from gram research quantities to larger requirements, with packaging suited to safe international transport. As a specialist exporter, Tech Serve Solutions arranges export documentation and shipping to most destinations, subject to applicable regulations in the destination country.
How do I request a sample or a quote?
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Contact Tech Serve Solutions with the product name, CAS number 898561-68-7 and your required quantity. We will confirm current availability, specification and lead time, and provide a formal quotation for samples or bulk supply.
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