N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide
N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide (CAS 179554-56-4; molecular formula C11H15IN2O; molar mass 318.15 g/mol) is a halogenated pyridine building block used in organic and medicinal chemistry research. It pairs an aryl iodide with a pivaloyl-protected aminopyridine, making it a versatile intermediate for cross-coupling and directed functionalisation. Tech Serve Solutions supplies this compound as a research-grade reagent to laboratories and fine-chemical manufacturers worldwide.
- Synonyms
- N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamideN-(5-Iodo-4-methylpyridin-2-yl)pivalamide2,2-Dimethyl-N-(5-iodo-4-methylpyridin-2-yl)propanamideN-(5-Iodo-4-methyl-2-pyridinyl)-2,2-dimethylpropanamideCAS 179554-56-4
Palladium-catalysed cross-coupling
The carbon-iodine bond provides a reactive handle for Suzuki, Stille, Sonogashira, Negishi and related couplings, allowing controlled introduction of aryl, alkenyl and alkynyl groups onto the pyridine ring.
Pharmaceutical and agrochemical intermediate
As a substituted aminopyridine, it serves as a heterocyclic building block in the synthesis of more complex molecules of interest in pharmaceutical and agrochemical discovery research.
Directed C-H functionalisation
The pivaloyl (2,2-dimethylpropanoyl) amide is a robust directing and protecting group, supporting regioselective metalation and ortho-functionalisation chemistry around the pyridine core.
Scaffold for library synthesis
The combination of a halogen handle and a protected amino group makes the compound a convenient starting point for parallel and medicinal-chemistry library work.
Laboratory research reagent
It is used as a reference and synthetic reagent in method development and exploratory route-scouting within academic and industrial laboratories.
| Molecular weight | 318.15 |
|---|---|
| Empirical formula | C11H15IN2O |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide used for?
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It is used primarily as a halogenated pyridine building block in organic and medicinal chemistry. The aryl iodide enables palladium-catalysed cross-coupling, while the pivaloyl-protected aminopyridine supports directed functionalisation, making it a useful intermediate in synthesis and research.
What is the CAS number and molecular formula of N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide?
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The CAS number is 179554-56-4. The molecular formula is C11H15IN2O (Hill notation) with a molecular weight of 318.15 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound as a research/technical-grade reagent for synthesis and laboratory use. We do not represent it as USP, BP or EP pharmacopoeial grade. A current Certificate of Analysis stating the actual assay and specification for each batch is available on request.
How should this compound be handled and stored?
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Specific GHS hazard data is not provided in our current record, so it should be treated as a research chemical of undefined hazard. Handle only with appropriate personal protective equipment in a well-ventilated laboratory, avoid dust and contact with skin and eyes, and store in a tightly closed container in a cool, dry place. Always consult the Safety Data Sheet supplied with the material before use.
How is N-(5-Iodo-4-methyl-pyridin-2-yl)-2,2-dimethyl-propionamide packed, shipped and exported?
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It is packed in suitable laboratory and bulk containers with full labelling and documentation, and exported worldwide. Packaging, quantities and shipping mode are confirmed per order, with the relevant Certificate of Analysis and Safety Data Sheet included.
How do I request a sample or quote?
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Contact Tech Serve Solutions with the product name or CAS number 179554-56-4 and your required quantity. We will respond with availability, lead time, documentation and a formal quotation, and can arrange a sample where appropriate.
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