N-(2-Methoxypyridin-3-yl)pivalamide
N-(2-Methoxypyridin-3-yl)pivalamide (CAS 125867-19-8) is a heterocyclic building block with the molecular formula C11H16N2O2 and a molar mass of 208.26 g/mol. It pairs a 2-methoxypyridine ring with a sterically hindered pivalamide group, making it a useful intermediate for organic and medicinal-chemistry synthesis. Tech Serve Solutions supplies it as a research-grade reagent to laboratories and process-development teams worldwide for use in directed metalation and the construction of substituted pyridine scaffolds.
- Synonyms
- N-(2-Methoxypyridin-3-yl)pivalamideN-(2-Methoxy-3-pyridinyl)-2,2-dimethylpropanamide2,2-Dimethyl-N-(2-methoxypyridin-3-yl)propanamideN-(2-Methoxypyridin-3-yl)-2,2-dimethylpropanamideCAS 125867-19-8
Pyridine building block
Serves as a functionalised 2-methoxypyridine intermediate for assembling more complex substituted pyridine scaffolds. Widely used in research-scale chemical synthesis where a pre-installed methoxy and amide handle are required.
Directed ortho-metalation substrate
The pivalamide is a classic directing group for directed ortho-metalation chemistry. It can facilitate regioselective lithiation and subsequent functionalisation around the pyridine ring.
Medicinal-chemistry intermediate
Used by discovery and process-development teams as a heterocyclic core for preparing candidate molecules and analogues. The protected 3-aminopyridine motif is a common feature in pharmaceutical intermediate work.
Amino-pyridine synthesis
Acts as a protected form of a 3-amino-2-methoxypyridine; the pivaloyl amide can be cleaved to reveal the free amine for onward coupling and derivatisation.
Reference and method development
Suitable as a research reagent for analytical method development and as a characterised reference compound in laboratory studies.
| Molecular weight | 208.26 |
|---|---|
| Empirical formula | C11H16N2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Methoxypyridin-3-yl)pivalamide used for?
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It is used as a heterocyclic building block and synthetic intermediate in organic and medicinal chemistry. The 2-methoxypyridine ring combined with a pivalamide directing group makes it useful for directed ortho-metalation and for constructing substituted pyridine and amino-pyridine scaffolds at research scale.
What is the CAS number and molecular formula of N-(2-Methoxypyridin-3-yl)pivalamide?
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The CAS number is 125867-19-8 and the molecular formula is C11H16N2O2 (Hill notation), corresponding to a molecular weight of 208.26 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply N-(2-Methoxypyridin-3-yl)pivalamide as a research/technical-grade reagent for laboratory and synthesis use. We do not represent it as a USP, BP or EP pharmacopoeial grade. A current specification and certificate of analysis can be provided on request so you can confirm assay and suitability before purchase.
How should N-(2-Methoxypyridin-3-yl)pivalamide be handled and stored?
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Handle it as a laboratory research chemical under good laboratory practice: avoid contact with skin and eyes, avoid dust formation, and work in a well-ventilated area with appropriate gloves and eye protection. Store the container tightly closed in a cool, dry place away from incompatible materials. No formal GHS classification is provided with our current data; consult the supplied safety documentation before use.
How is N-(2-Methoxypyridin-3-yl)pivalamide packed, shipped and exported?
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It is packed in appropriately sealed and labelled containers sized to the order, from gram quantities to larger research lots. As a specialist exporter, Tech Serve Solutions arranges compliant international documentation and dispatch to laboratories and manufacturers worldwide.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 125867-19-8. We will respond with availability, a current specification, lead time and a formal quotation, and can arrange a sample where appropriate.
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