N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide
N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide (CAS 1142192-30-0) is a halogenated pyridine building block with the molecular formula C10H13BrN2O2 and a molar mass of 273.13 g/mol. It combines a bromo substituent, a free hydroxy group and a pivaloyl-protected amine on a single pyridine ring, giving multiple orthogonal handles for selective functionalisation. Tech Serve Solutions supplies it as a research-grade fine chemical for synthetic and medicinal-chemistry programmes.
- Synonyms
- N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamideN-(2-bromo-5-hydroxy-3-pyridinyl)-2,2-dimethylpropanamide2,2-dimethyl-N-(2-bromo-5-hydroxypyridin-3-yl)propanamideCAS 1142192-30-0
Heterocyclic building block
Serves as a multifunctional pyridine scaffold in chemical synthesis, where its bromo, hydroxy and protected-amino groups allow stepwise, selective elaboration into more complex molecules.
Cross-coupling substrate
The aryl bromide provides a reactive site for palladium-catalysed couplings such as Suzuki-Miyaura, Buchwald-Hartwig and related carbon-carbon and carbon-heteroatom bond formations.
Medicinal-chemistry intermediate
Functionalised aminopyridines of this type are commonly used as intermediates in pharmaceutical discovery and structure-activity studies. We supply the material for research use and make no therapeutic claims.
Pivaloyl-protected amine handle
The pivalamide masks the ring amine during downstream transformations and can be removed under hydrolytic conditions to reveal the free aminopyridine for further derivatisation.
Hydroxypyridine for O-functionalisation
The free hydroxy group offers a site for O-alkylation, acylation or triflation, enabling the assembly of ethers, esters and additional coupling partners on the ring.
| Molecular weight | 273.13 |
|---|---|
| Empirical formula | C10H13BrN2O2 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide used for?
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It is used mainly as a halogenated pyridine building block and synthetic intermediate. The reactive bromide, free hydroxy group and pivaloyl-protected amine make it a versatile scaffold for cross-coupling chemistry and medicinal-chemistry research.
What is the CAS number and molecular formula of N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide?
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The CAS number is 1142192-30-0 and the molecular formula is C10H13BrN2O2, corresponding to a molecular weight of 273.13 g/mol.
What grade and purity does Tech Serve Solutions supply?
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We supply N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide as a research-grade fine chemical for synthesis. A specific assay is not stated here, so please request the current specification or certificate of analysis for the available lot. We do not represent this material as USP, BP or EP grade.
How should N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide be handled and stored?
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No GHS classification is provided for this item, so it should be treated as a research chemical of undetermined hazard. Handle it only with suitable laboratory controls, gloves and eye protection, avoid dust and contact, and store it cold and dry in a tightly closed container. Always confirm with our safety data sheet before use.
How is N-(2-Bromo-5-hydroxypyridin-3-yl)pivalamide packed, shipped and exported?
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It is packed in sealed, labelled containers sized to your order, from gram to bulk quantities, with appropriate inner protection. As a global supplier and exporter since 1998, Tech Serve Solutions arranges compliant documentation and worldwide despatch to laboratory and industrial customers.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, packaging and destination, quoting CAS 1142192-30-0. We will confirm availability, current specifications and lead time, and provide a quotation for samples or bulk supply.
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