Methyl tetrahydro-2H-pyran-4-carboxylate
Methyl tetrahydro-2H-pyran-4-carboxylate (CAS 110238-91-0) is a saturated oxygen-heterocyclic ester with the molecular formula C7H12O3 and a molar mass of 144.17 g/mol. Supplied as a liquid of ≥98.0% (GC) purity, it is a versatile tetrahydropyran building block used in chemical synthesis. The tetrahydropyran ring and reactive methyl ester make it a useful intermediate in pharmaceutical and agrochemical research. Tech Serve Solutions supplies and exports this reagent worldwide.
- IUPAC
- THPE
- Synonyms
- Methyl tetrahydro-2H-pyran-4-carboxylateMethyl tetrahydropyran-4-carboxylateMethyl oxane-4-carboxylateTetrahydro-2H-pyran-4-carboxylic acid methyl esterTetrahydropyran-4-carboxylic acid methyl esterMethyl 4-tetrahydropyrancarboxylate
Heterocyclic building block
Serves as a saturated tetrahydropyran (oxane) scaffold for constructing more complex molecules. The pre-formed, stable six-membered oxygen ring is a common motif introduced to tune the properties of target compounds.
Pharmaceutical intermediate
Used as an intermediate in medicinal chemistry and pharmaceutical research and development. The tetrahydropyran-4-yl group is a recognised structural element in many drug-discovery programmes.
Ester for further functionalisation
The methyl ester is a convenient handle for downstream transformations such as hydrolysis to the carboxylic acid, reduction to the alcohol, or conversion to amides. This makes it a flexible precursor in multistep synthesis.
Agrochemical and fine-chemical synthesis
Applied as a general building block in the preparation of agrochemicals, specialty chemicals and other fine-chemical targets where a functionalised tetrahydropyran unit is required.
Laboratory reagent
Used in research laboratories as a reference building block and synthetic reagent for exploratory and route-development work.
| Molecular weight | 144.17 |
|---|---|
| Empirical formula | C7H12O3 |
| Assay | ≥98.0% (GC) |
| Grade | produced by BASF |
| Density | 1.080 g/mL at 20 °C(lit.) |
Hazard statements
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 86 °C / 186.8 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl tetrahydro-2H-pyran-4-carboxylate used for?
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It is used mainly as a building block and intermediate in chemical synthesis. The combination of a saturated tetrahydropyran (oxane) ring and a reactive methyl ester makes it valuable in pharmaceutical, agrochemical and fine-chemical research, where it can be elaborated into more complex molecules.
What is the CAS number and molecular formula of Methyl tetrahydro-2H-pyran-4-carboxylate?
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The CAS number is 110238-91-0 and the molecular formula is C7H12O3, corresponding to a molecular weight of 144.17 g/mol. Its MDL number is MFCD01075170 and its Beilstein registry number is 114974.
What grade and purity does Tech Serve Solutions supply?
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We supply Methyl tetrahydro-2H-pyran-4-carboxylate at a minimum assay of ≥98.0% by GC, as a research and synthesis-grade building block. We do not represent it as a USP, BP or EP pharmacopoeia grade. A certificate of analysis is provided with each batch, and full specifications are available on request.
What are the safety and handling precautions for this compound?
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It is classified under GHS07 with the signal word Warning and hazard statement H319 (causes serious eye irritation). Wear suitable eye protection and gloves, and avoid contact with the eyes; if exposure occurs, rinse cautiously with water for several minutes and remove contact lenses if present (P305 + P351 + P338). It is a combustible liquid with a flash point of about 86 °C, and it carries a German Water Hazard Class (WGK) of 2. Always consult the Safety Data Sheet before use.
How is Methyl tetrahydro-2H-pyran-4-carboxylate packed, shipped and exported?
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It is packed in appropriately sealed containers sized to the order, from laboratory quantities to bulk, with full labelling and a certificate of analysis. As a global supplier and exporter, Tech Serve Solutions arranges compliant documentation and international shipping in line with the applicable transport regulations.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and our team will provide a quotation, available packaging options and lead time. Samples can be arranged on request, subject to availability.
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