Methyl pyrimidine-5-carboxylate
Methyl pyrimidine-5-carboxylate (CAS 34253-01-5) is a heterocyclic building block with the molecular formula C6H6N2O2 and a molecular weight of 138.12 g/mol. It is the methyl ester of pyrimidine-5-carboxylic acid, supplied as a crystalline solid melting at 76-81 °C. The reactive ester group on an electron-poor pyrimidine ring makes it a versatile intermediate for medicinal chemistry and chemical synthesis. Tech Serve Solutions supplies and exports this reagent-grade compound worldwide.
- Synonyms
- Methyl pyrimidine-5-carboxylatePyrimidine-5-carboxylic acid methyl esterMethyl 5-pyrimidinecarboxylate5-Pyrimidinecarboxylic acid methyl ester
Pharmaceutical intermediate
Serves as a heterocyclic building block in the synthesis of pyrimidine-based drug candidates and active pharmaceutical ingredients. The pyrimidine core is a privileged scaffold across many therapeutic classes.
Heterocyclic building block
Used in multi-step organic synthesis to introduce a functionalised pyrimidine unit. The methyl ester provides a convenient handle for amidation, hydrolysis, reduction and transesterification.
Agrochemical research
Pyrimidine carboxylates feature in the discovery of crop-protection agents. This compound can act as a precursor in exploratory agrochemical synthesis programmes.
Medicinal chemistry and library synthesis
Suited to discovery-scale work where the ester is elaborated into amides, acids and related derivatives for structure-activity studies and compound libraries.
Laboratory reference and synthesis reagent
Employed in research laboratories as a defined-purity reagent for method development and small-scale preparative chemistry.
| Molecular weight | 138.12 |
|---|---|
| Empirical formula | C6H6N2O2 |
| Assay | 95% |
| Melting point | 76-81 °C |
Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 37/38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Methyl pyrimidine-5-carboxylate used for?
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It is used mainly as a heterocyclic building block and intermediate in chemical synthesis, including pharmaceutical and agrochemical research. The methyl ester on an electron-poor pyrimidine ring is readily converted into amides, carboxylic acids and other derivatives during multi-step synthesis.
What is the CAS number and molecular formula of Methyl pyrimidine-5-carboxylate?
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The CAS number is 34253-01-5 and the molecular formula is C6H6N2O2. Its molecular weight is 138.12 g/mol, the MDL number is MFCD06204205, and it melts at 76-81 °C.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Methyl pyrimidine-5-carboxylate at a typical assay of 95% as a research and synthesis reagent. We do not represent it as USP, BP or EP pharmacopoeia grade; a batch-specific certificate of analysis is provided on request.
What are the safety and handling requirements for Methyl pyrimidine-5-carboxylate?
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It is classified as hazardous (GHS05, GHS07; signal word Danger). It causes skin irritation (H315), causes serious eye damage (H318) and may cause respiratory irritation (H335). Handle with gloves, eye shields and an N95-type dust mask, avoid dust formation, and consult the Safety Data Sheet before use. WGK Germany water-hazard class is 3.
How is Methyl pyrimidine-5-carboxylate packed, shipped and exported?
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It is packed as a solid in sealed containers sized to the order, from gram quantities to bulk, with full labelling and documentation. Tech Serve Solutions ships and exports worldwide in compliance with applicable transport and dangerous-goods regulations; the SDS and certificate of analysis accompany each consignment.
How do I request a sample or quote?
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Contact Tech Serve Solutions with your required quantity, purity and destination, and we will respond with availability, lead time and a quotation. Samples can be arranged for qualified buyers, subject to availability.
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