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Methyl indole-3-acetate

CAS 1912-33-0C11H11NO2Heterocyclic Building Blocks

Methyl indole-3-acetate (CAS 1912-33-0; C11H11NO2; molar mass 189.21 g/mol) is the methyl ester of indole-3-acetic acid, the natural plant auxin. It is a low-melting crystalline indole solid (m.p. 50-52 degC) soluble in methanol, supplied at high purity for research and synthesis. As a versatile heterocyclic building block it serves indole chemistry, auxin and plant-physiology studies, and the preparation of more elaborate indole derivatives.

IUPAC
Indole-3-acetic acid methyl ester,Methyl 3-indolylacetate
Synonyms
Methyl indole-3-acetateIndole-3-acetic acid methyl esterMethyl 3-indolylacetateMethyl 1H-indol-3-ylacetateIAA methyl ester
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Methyl indole-3-acetate (C11H11NO2) — chemical structure, CAS 1912-33-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC11Chemical SynthesisHeterocyclic Building BlocksIndoles
01 /Applications

Indole building block for organic synthesis

Used as a C11 heterocyclic building block in chemical synthesis, providing a reactive indole nucleus and an esterified acetic-acid side chain for onward functionalisation. It is a convenient intermediate towards substituted indoles and related fine-chemical structures.

Auxin and plant-physiology research

As the methyl ester of the natural auxin indole-3-acetic acid (IAA), it is employed in laboratory studies of auxin chemistry, metabolism and signalling. The ester form is widely used as a reference and starting material in plant-growth research.

Reference and analytical standard

Its high GC assay and well-defined identity make it suitable as a reference material for chromatographic and spectroscopic method development relating to indole and auxin analysis. Identity is supported by defined CAS, MDL and Beilstein registry numbers.

Precursor to indole-3-acetic acid derivatives

The ester can be hydrolysed or transesterified to access indole-3-acetic acid and related conjugates, or carried forward in multi-step routes. This makes it a practical handle for assembling more complex indole-acetate chemistry.

02 /Properties
Molecular weight189.21
Empirical formulaC11H11NO2
Assay≥99.0% (GC)
Boiling point160-163 °C/0.5 mmHg
Solubilitymethanol: soluble0.1 g/mL, clear
Storage temperature2-8°C
Melting point50-52 °C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
1912-33-0
MDL number
MFCD00022749
Beilstein registry
158031
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Methyl indole-3-acetate used for?

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Methyl indole-3-acetate is used mainly as a heterocyclic indole building block in organic and medicinal-chemistry synthesis, and as a research material in auxin and plant-physiology studies, since it is the methyl ester of the natural plant hormone indole-3-acetic acid. It also serves as a reference and as a precursor to indole-3-acetic acid derivatives.

What is the CAS number and molecular formula of Methyl indole-3-acetate?

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The CAS number is 1912-33-0 and the molecular formula is C11H11NO2, with a molecular weight of 189.21 g/mol. Related identifiers include EC number 217-622-5, MDL number MFCD00022749 and Beilstein registry number 158031.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Methyl indole-3-acetate at a purity of at least 99.0% by GC, as a research and laboratory-reagent grade material. We do not represent it as USP, BP or EP pharmacopoeial grade; a Certificate of Analysis is provided with each batch.

How should Methyl indole-3-acetate be stored and handled?

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Store the product refrigerated at 2-8 degC in a tightly closed container, away from moisture and incompatible materials. It is classified as German water-hazard class WGK 3 (severely hazardous to water), so prevent release to drains, soil and watercourses. Use eye protection, gloves and a suitable particulate respirator (N95/P1), and consult the Safety Data Sheet before use.

How is Methyl indole-3-acetate packed, shipped and exported?

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It is packed in appropriately sealed laboratory and bulk containers, labelled and accompanied by a Certificate of Analysis and Safety Data Sheet. As a temperature-sensitive item it is dispatched with suitable cool handling where required, and Tech Serve Solutions exports worldwide with full documentation in line with the destination country's import requirements.

How do I request a sample or quote for Methyl indole-3-acetate?

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Contact Tech Serve Solutions with your required quantity, packaging and destination, and our team will respond with availability, lead time and a formal quotation. Samples can be arranged on request, subject to availability and applicable shipping requirements.

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