Meglumine
Meglumine (CAS 6284-40-8), a derivative of sorbitol, is an organic compound with the formula C7H17NO5 and a molecular weight of 195.21 g/mol. This white crystalline powder is known for its solubility in water and is primarily utilised in pharmaceutical formulations as a solubilising agent and counter-ion. Its chemical properties also lend themselves to applications in analytical chemistry and biochemical research.
- IUPAC
- Meglumine
Pharmaceutical Excipient
Meglumine serves as an essential excipient in the pharmaceutical industry. It is widely employed to enhance the solubility of poorly soluble active pharmaceutical ingredients (APIs), facilitating their formulation into effective dosage forms. It also acts as a counter-ion, forming salts that can improve drug stability and bioavailability.
Radiocontrast Agent Component
In medical imaging, meglumine is a key component in certain radiocontrast agents. It forms salts with iodinated acids, creating water-soluble compounds that are safely administered to patients for diagnostic procedures like X-rays and CT scans.
Analytical Reagent
Meglumine finds application as a reagent in analytical chemistry. Its specific chemical properties allow it to be used in various titrations and chromatographic methods, contributing to accurate chemical analysis and quality control in laboratory settings.
Biochemical Research
As a carbohydrate derivative, meglumine is utilised in biochemical research. Its interactions within biological systems and its role as a buffer or solubilising agent make it a useful tool for scientists investigating cellular processes and developing new biotechnological applications.
| Molecular weight | 195.21 |
|---|---|
| Empirical formula | C7H17NO5 |
| Assay | 99.0-100.5% (titration) |
| Solubility | H2O: soluble0.1 g/mL, clear, colorless |
| Optical activity | [α]20/D −16.5±0.5°, c = 2% in H2O |
| Autoignition temp | ~662 °F |
| Suitability | meets USP testing specifications |
| Melting point | 129-131.5 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Cation traces | Ca: ≤10 mg/kgCd: ≤5 mg/kgCo: ≤5 mg/kgCr: ≤5 mg/kgCu: ≤5 mg/kgFe: ≤5 mg/kgK: ≤50 mg/kgMg: ≤5 mg/kgMn: ≤5 mg/kgMo: ≤5 mg/kgNa: ≤50 mg/kgNi: ≤20 mg/kgPb: ≤5 mg/kgZn: ≤5 mg/kg |
| Anion traces | chloride (Cl-): ≤50 mg/kgphosphate (PO43-): ≤5 mg/kgsulfate (SO42-): ≤50 mg/kg |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Meglumine used for?
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Meglumine is primarily used as a pharmaceutical excipient to improve drug solubility and as a counter-ion in contrast media for medical imaging. It also finds applications in analytical chemistry and biochemical research.
What are the CAS number and formula for Meglumine?
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The CAS number for Meglumine is 6284-40-8, and its chemical formula is C7H17NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Meglumine with an assay of 99.0-100.5% (titration). We do not represent this product as USP, BP, or EP grade unless explicitly stated in the product specifications.
How should Meglumine be handled and stored?
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Handling Meglumine requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter. Store in a well-ventilated area away from ignition sources, as it has a high autoignition temperature of approximately 662 °F.
Is Meglumine a controlled substance?
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The provided data does not indicate that Meglumine is a controlled substance.
How is Meglumine shipped and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export details for Meglumine can be provided upon request, adhering to all relevant international regulations.
How can I request a quote or sample of Meglumine?
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To request a quote or a sample of Meglumine, please contact our sales team through the website or directly via the provided contact information.
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