Dimethyl sulfoxide
Dimethyl sulfoxide (DMSO), CAS 67-68-5, with a molecular weight of 78.13 g/mol, is a highly polar aprotic solvent. It is known for its exceptional ability to dissolve a wide range of organic and inorganic compounds. DMSO finds extensive application in chemical synthesis, as a cryoprotectant in cell culture, and as a penetration enhancer in various formulations. Its versatile properties make it invaluable in research and industrial settings.
- IUPAC
- DMSO,Methyl sulfoxide
- Synonyms
- DMSODimethyl sulphoxideMethyl sulfoxide1-Thia-4-oxacyclohexane 1,1-dioxideSulfoxide, dimethylDimethylSufoxide
Solvent in Organic Synthesis
Dimethyl sulfoxide is widely used as a polar aprotic solvent for numerous organic reactions, facilitating reactions such as nucleophilic substitutions and oxidations due to its high dielectric constant and ability to stabilise transition states.
Cryoprotectant
In biological and medical research, DMSO is commonly employed as a cryoprotective agent to prevent damage to cells and tissues during freezing and storage at ultra-low temperatures.
Penetration Enhancer
DMSO's ability to readily permeate biological membranes makes it useful as a penetration enhancer in topical formulations and drug delivery systems.
Analytical Applications
It serves as a crucial reagent in various analytical techniques, including chromatography and as a solvent for biochemical assays and enzyme studies.
| Molecular weight | 78.13 |
|---|---|
| Linear formula | (CH3)2SO |
| Assay | ≥99.5% (GC) |
| Grade | puriss. p.a. |
| Boiling point | 189 °C(lit.) |
| Density | 1.10 g/mL(lit.) |
| Refractive index | n20/D 1.479(lit.)n20/D 1.479 |
| Melting point | 16-19 °C(lit.) |
| Vapour pressure | 0.42 mmHg (20 °C) |
| Vapour density | 2.7 (vs air) |
| Autoignition temp | 573 °F |
| Storage temperature | room temp |
| Impurities tested | Dnases, none detectedRNases, none detectedinsoluble matter, passes filter testphosphatases, none detectedproteases, none detected≤0.001% free acid (as CH3COOH) |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Expl Lim | 42 %, 63 °F |
|---|---|
| Evapn Residue | ≤0.005% |
| Uv Absorption | λ: 280 nm Amax: 0.22 |
| Absorption | UV absorption/ passes test |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dimethyl Sulfoxide (DMSO) used for?
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Dimethyl sulfoxide is used as a versatile polar aprotic solvent in organic synthesis, a cryoprotectant for cells and tissues, a penetration enhancer in formulations, and in various analytical and biochemical applications.
What is the CAS number and molecular formula for Dimethyl Sulfoxide?
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The CAS number for Dimethyl Sulfoxide is 67-68-5, and its linear formula is (CH3)2SO.
What grade and purity does Tech Serve Solutions supply for Dimethyl Sulfoxide?
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Tech Serve Solutions supplies Dimethyl Sulfoxide with a purity of ≥99.5% (GC), in Puriss. p.a. grade. It is not represented as USP, BP, or EP grade unless explicitly stated.
What are the primary safety hazards associated with Dimethyl Sulfoxide?
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Dimethyl sulfoxide is flammable and has a flash point of 87 °C (188.6 °F). It requires appropriate handling with personal protective equipment, including eyeshields and suitable respirator cartridges, to mitigate risks.
How is Dimethyl Sulfoxide packed, shipped, and exported by TSS?
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Dimethyl Sulfoxide is supplied in plastic bottles and is available for global export. Specific packaging and shipping details can be provided upon request.
How can I request a sample or quote for Dimethyl Sulfoxide?
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To request a sample or quote for Dimethyl Sulfoxide, please contact our sales team through the website or provide your details via the inquiry form.
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