1-Boc-4-piperidylacetic acid
1-Boc-4-piperidylacetic acid (CAS: 157688-46-5), with the molecular formula C12H21NO4 and a molecular weight of 243.30 g/mol, is a valuable intermediate in organic synthesis. It is particularly useful in the development of novel pharmaceuticals and in peptide chemistry. Its structure facilitates the introduction of a piperidine moiety with an acetic acid side chain, enabling diverse chemical transformations.
- IUPAC
- 1-Boc-4-piperidineacetic acid

Pharmaceutical Intermediate
This compound serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs). Its unique structure allows for the incorporation of piperidine rings, a common feature in many therapeutic agents.
Peptide Chemistry
In peptide synthesis, 1-Boc-4-piperidylacetic acid can be used to introduce non-natural amino acid derivatives. This aids in the creation of peptides with modified structures and potentially enhanced biological properties.
Chemical Synthesis Reagent
It is employed as a versatile reagent in various organic synthesis pathways, facilitating complex molecular constructions. The Boc protecting group allows for controlled reactions and selective deprotection strategies.
Research and Development
This chemical is utilized in academic and industrial research settings for exploring new synthetic methodologies and discovering novel compounds with potential applications in medicinal chemistry and materials science.
| Molecular weight | 243.30 |
|---|---|
| Empirical formula | C12H21NO4 |
| Assay | ≥98.0% (TLC) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 1-Boc-4-piperidylacetic acid used for?
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1-Boc-4-piperidylacetic acid is primarily used as an intermediate in chemical synthesis, particularly in the fields of pharmaceutical development and peptide chemistry, for the construction of complex organic molecules.
What are the CAS number and formula for 1-Boc-4-piperidylacetic acid?
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The CAS number is 157688-46-5, and the empirical formula is C12H21NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 1-Boc-4-piperidylacetic acid with an assay of ≥98.0% (TLC). This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for 1-Boc-4-piperidylacetic acid?
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This compound is classified with GHS07 and a Warning signal word, with hazard statements H315, H319, and H335, indicating it may cause skin irritation, serious eye irritation, and respiratory irritation. Use with a dust mask type N95 (US), eyeshields, and gloves in a well-ventilated area, adhering to precautionary statements like P261 and P305 + P351 + P338.
How is 1-Boc-4-piperidylacetic acid shipped and exported?
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Tech Serve Solutions, a global supplier and exporter since 1998, offers 1-Boc-4-piperidylacetic acid for export worldwide, adhering to all relevant shipping and customs regulations for chemical materials.
How can I request a sample or quote for 1-Boc-4-piperidylacetic acid?
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To request a sample or obtain a quote for 1-Boc-4-piperidylacetic acid, please contact our sales department through the website or by phone, providing your specific requirements.
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