Z-Trp-Bt
Z-Trp-Bt (CAS: 850232-59-6, Formula: C25H21N5O3, MW: 439.47 g/mol) is a benzotriazole amino acid derivative. It serves as a versatile reagent in chemical synthesis, particularly for the construction of peptides, peptidomimetics, and conjugates. Its applications span chemical biology and advanced peptide chemistry, facilitating the development of complex molecular structures.
- IUPAC
- (S)-N-Z-1-Benzotriazolylcarbonyl-2-(3-indolyl)ethylamine,(S)-Benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate
- Synonyms
- (S)-N-Z-1-Benzotriazolylcarbonyl-2-(3-indolyl)ethylamine(S)-Benzyl (1-(1H-benzo[d][1,2,3]triazol-1-yl)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)carbamate
Peptide Synthesis
Used as a building block or reagent in the synthesis of peptides and peptide analogues. Its benzotriazole moiety can act as an activating group or a handle for further modifications.
Peptidomimetics Development
Facilitates the creation of peptidomimetics, such as aminoxypeptides and depsipeptides, which mimic the structure or function of natural peptides but with enhanced stability or altered properties.
Bioconjugation Chemistry
Enables the preparation of tagged peptides and peptide conjugates, including those linked to fluorescent labels or other moieties via N, O, S, or C atoms.
Chemical Biology Research
A valuable tool for researchers investigating biological systems through the synthesis of modified peptides or peptide-like molecules for probing biological pathways.
| Molecular weight | 439.47 |
|---|---|
| Empirical formula | C25H21N5O3 |
| Assay | 95% |
| Storage temperature | −20°C |
| Application | Benzotriazole amino acids, or aminoacylbenzotriazolides, are versatile reagents for synthesizing peptides as well as their mimetics and conjugates. Benzotriazole amino acids have been used for the preparation of diverse derivatives including:• Polypeptidal benzotriazolides1• Peptidomimetics, such as aminoxypeptides2, depsipeptides3 and heterocyclic peptidomimetics4• Tagged peptides and peptidomimetics, particularly those with fluorescent labels5,6• N, O, S, and C linked peptide conjugates6 |
| Melting point | 100-107 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Z-Trp-Bt used for?
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Z-Trp-Bt is primarily used in chemical synthesis for the preparation of peptides, peptidomimetics, and bioconjugates. It is valuable in research for chemical biology and peptide chemistry applications.
What are the CAS number and formula for Z-Trp-Bt?
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The CAS number for Z-Trp-Bt is 850232-59-6, and its empirical formula is C25H21N5O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Z-Trp-Bt with a minimum purity of 95% (Assay: 95%). This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia applications.
How should Z-Trp-Bt be handled and stored?
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Z-Trp-Bt is classified as a warning substance (GHS07) and may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, avoiding inhalation and contact with skin and eyes. Store at -20°C.
Is Z-Trp-Bt a controlled substance?
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Based on the provided data, Z-Trp-Bt is not indicated as a controlled substance.
How can I request a sample or quote for Z-Trp-Bt?
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To request a sample or obtain a quote for Z-Trp-Bt, please contact the Tech Serve Solutions sales team through the website or by phone.
How is Z-Trp-Bt packed and exported?
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Z-Trp-Bt is packed according to industry standards for chemical reagents and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
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