Z-His(Bzl)-OH

CAS 21929-66-8C21H21N3O4Biochemicals & Reagents

Z-His(Bzl)-OH (CAS 21929-66-8), with the molecular formula C21H21N3O4 and a molecular weight of 379.41 g/mol, is a protected derivative of the amino acid histidine. This compound is valuable in peptide synthesis due to the benzyl protection on the imidazole nitrogen and the benzyloxycarbonyl (Z) protecting group on the alpha-amino group, facilitating controlled coupling reactions. It is primarily utilised in research and development settings for the construction of complex peptides and proteins.

IUPAC: Nα-Cbz-Nim-benzyl-L-histidine,Nα-Z-N(im)-benzyl-L-histidine
Synonyms: Nα-Cbz-Nim-benzyl-L-histidineNα-Z-N(im)-benzyl-L-histidine

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Z-His(Bzl)-OH (C21H21N3O4) — chemical structure, CAS 21929-66-8; Life Science, fine chemical supplied by Tech Serve Solutions

Amino AcidsBiochemicals and ReagentsModified Amino Acids

01 /Applications

Peptide Synthesis

Utilised as a protected building block in solid-phase or solution-phase peptide synthesis. The Z and benzyl protecting groups allow for selective deprotection and controlled chain elongation, crucial for creating specific peptide sequences.

Biochemical Research

Serves as a reagent in studies involving modified amino acids and their incorporation into peptides. This allows researchers to investigate the structure-activity relationships of peptides containing modified histidine residues.

Drug Discovery and Development

A key intermediate in the synthesis of novel peptide-based therapeutics or diagnostic agents. Its specific structure enables the creation of complex molecules with potential biological activity.

02 /Properties

Molecular weight	379.41
Empirical formula	C21H21N3O4
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

21929-66-8

MDL number

MFCD00037892

Beilstein registry

55593

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Z-His(Bzl)-OH used for?

Z-His(Bzl)-OH is primarily used as a protected amino acid building block in chemical peptide synthesis and biochemical research.

What are the CAS number and molecular formula for Z-His(Bzl)-OH?

The CAS number for Z-His(Bzl)-OH is 21929-66-8, and its molecular formula is C21H21N3O4.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Z-His(Bzl)-OH for research and laboratory use. The specific grade and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.

How should Z-His(Bzl)-OH be handled and stored?

Handle Z-His(Bzl)-OH with appropriate personal protective equipment, including eyeshields and gloves. It should be stored at -20°C. Refer to the Safety Data Sheet (SDS) for detailed handling and hazard information.

How is Z-His(Bzl)-OH shipped and exported?

Z-His(Bzl)-OH is carefully packaged and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical compounds.

How can I request a quote or sample for Z-His(Bzl)-OH?

To request a quote or a sample of Z-His(Bzl)-OH, please contact our sales department through the TSS website or by phone, providing your specific requirements.