Tris(o-methoxyphenyl)phosphine
Tris(o-methoxyphenyl)phosphine (CAS: 4731-65-1; C21H21O3P) is a phosphine compound with a molecular weight of 352.36 g/mol. Supplied by Tech Serve Solutions with an assay of 96%, this chemical serves as a versatile catalyst in various organic synthesis reactions. Its applications span allylic substitution, Suzuki coupling, telomerization, hydrogenation, and amination/direct arylation processes, making it a valuable reagent in catalysis and chemical synthesis.
- IUPAC
- NSC 93545,Tris(o-anisyl)phosphine
- Synonyms
- Tris(o-anisyl)phosphine
Catalyst for Allylic Substitution
Tris(o-methoxyphenyl)phosphine catalyses the allylic substitution of simple alkenes, offering a pathway for functionalizing olefinic compounds.
Suzuki Coupling Reactions
This phosphine ligand is employed as a catalyst in Suzuki coupling reactions, facilitating the formation of carbon-carbon bonds critical in organic synthesis.
Telomerization of Butadiene
It acts as a catalyst for the telomerization of 1,3-butadiene with various alcohols, a process useful for creating functionalized dienes.
Hydrogenation of Quinolines
The compound can be used as a catalyst in the hydrogenation of quinolines, a key transformation in the synthesis of nitrogen-containing heterocyclic compounds.
Amination and Direct Arylation
Tris(o-methoxyphenyl)phosphine is utilised in amination and direct arylation reactions, enabling the introduction of amine or aryl groups into organic molecules.
| Molecular weight | 352.36 |
|---|---|
| Empirical formula | C21H21O3P |
| Assay | 96% |
| Application | Catalyst for:• Allylic substitution of simple alkenes1• Suzuki coupling reactions2• Telomerization of 1,3-butadiene with various alcohols3• Hydrogenation of quinolines4• Amination / direct arylation5 |
| Melting point | 198-204 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H413May cause long-lasting harmful effects to aquatic life
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(o-methoxyphenyl)phosphine used for?
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Tris(o-methoxyphenyl)phosphine is primarily used as a catalyst in various organic synthesis reactions, including allylic substitution, Suzuki coupling, telomerization of butadiene, hydrogenation of quinolines, and amination/direct arylation.
What is the CAS number and chemical formula for Tris(o-methoxyphenyl)phosphine?
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The CAS number for Tris(o-methoxyphenyl)phosphine is 4731-65-1, and its chemical formula is C21H21O3P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(o-methoxyphenyl)phosphine with an assay of 96%. This product is intended for research and chemical synthesis purposes and is not represented as meeting USP, BP, EP, or pharmacopoeia standards.
How should Tris(o-methoxyphenyl)phosphine be handled safely?
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Handle with care as Tris(o-methoxyphenyl)phosphine is a Warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Prolonged contact may cause harm to aquatic life with long lasting effects (H413). Use a dust mask type N95 (US), wear eyeshields and gloves. Ensure adequate ventilation. Avoid breathing dust.
How is Tris(o-methoxyphenyl)phosphine packed and shipped?
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Tris(o-methoxyphenyl)phosphine is carefully packaged to maintain its integrity during transit. Tech Serve Solutions exports globally, adhering to all relevant shipping regulations for chemical compounds.
How can I request a sample or quote for Tris(o-methoxyphenyl)phosphine?
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To request a sample or a quote for Tris(o-methoxyphenyl)phosphine, please contact our sales team via the website or by phone. Provide your specific requirements for prompt assistance.
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