Tris(hydroxymethyl)aminomethane
Tris(hydroxymethyl)aminomethane (CAS 77-86-1), molecular formula NH2C(CH2OH)3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.
- IUPAC
- 2-Amino-2-(hydroxymethyl)-1,3-propanediol,THAM,Tris base,Tris(hydroxymethyl)aminomethane,Trometamol,Trometamolum

| Molecular weight | 121.14 |
|---|---|
| Linear formula | NH2C(CH2OH)3 |
| Assay | ≥99.8% |
| Grade | ACS reagent |
| Boiling point | 219-220 °C/10 mmHg(lit.) |
| Solubility | water: soluble678 g/L at 20 °C |
| pH | 10.5-12.0 (25 °C, 4 M in H2O) |
| Melting point | 167-172 °C(lit.) |
| Loss on drying | ≤0.5% loss on drying, 110 °C |
| Impurities tested | ≤0.2% water (Karl Fischer) |
| Suitability | in accordance for luminescence |
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Cation traces | heavy metals (as Pb): ≤2 ppm |
| Anion traces | chloride (Cl-): ≤20 mg/kgsulfate (SO42-): ≤5 mg/kg |
| Ignition residue | ≤0.01% (as SO4) |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Pka 25 °C | 8.1 |
|---|---|
| Uv Absorption | λ: 260 nm Amax: 0.10λ: 280 nm Amax: 0.08 |
| Absorption | A40%/290 nm ≤0.05 |
| Ph Range | 7 - 9 |
| Useful Ph Range | 7 - 9 |
Documentation
Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(hydroxymethyl)aminomethane?
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Tris(hydroxymethyl)aminomethane (CAS 77-86-1), molecular formula NH2C(CH2OH)3, is a high-purity chemical supplied by Tech Serve Solutions for chemical synthesis applications, to USP, BP and EP standards.
What grades of Tris(hydroxymethyl)aminomethane does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(hydroxymethyl)aminomethane in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.
What is the CAS number and molecular formula of Tris(hydroxymethyl)aminomethane?
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Tris(hydroxymethyl)aminomethane has CAS number 77-86-1 and molecular formula NH2C(CH2OH)3. Full specifications appear in the table above and in the Certificate of Analysis.
What is the typical minimum order quantity and lead time for Tris(hydroxymethyl)aminomethane?
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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.
Do you provide a Certificate of Analysis (CoA) with each shipment?
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Yes. Every batch of Tris(hydroxymethyl)aminomethane ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.
How should Tris(hydroxymethyl)aminomethane be stored?
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Store Tris(hydroxymethyl)aminomethane in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.
What is Tris(hydroxymethyl)aminomethane used for?
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Tris(hydroxymethyl)aminomethane is used in chemical synthesis applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.
How do I request a quote for Tris(hydroxymethyl)aminomethane?
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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.
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