Tris(dimethylamino)methane
Tris(dimethylamino)methane (CAS: 5762-56-1), with the molecular formula [(CH3)2N]3CH and a molar mass of 145.25 g/mol, is a versatile organic compound. It functions as a key reagent in chemical synthesis. This compound is frequently employed for the preparation of nucleoside analogs, as a tool for introducing the dimethylaminoethylidene group, and in ring-opening polymerisation processes. Supplied by Tech Serve Solutions for research and development purposes.
![Tris(dimethylamino)methane ([(CH3)2N]3CH) — chemical structure, CAS 5762-56-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F5762-56-1.png&w=3840&q=75)
Nucleoside Analog Synthesis
Tris(dimethylamino)methane has been utilised in the synthesis of phosphoramidite derivatives, enabling the preparation of novel nucleoside analogues for further research.
Dimethylaminoethylidene Group Introduction
This compound serves as a reagent for effectively introducing the dimethylaminoethylidene group into various molecular structures during synthetic procedures.
Ring-Opening Polymerisation
In polymer chemistry, Tris(dimethylamino)methane has been applied as a reagent in the ring-opening (RO) polymerisation of lactide, contributing to the formation of specific polymer architectures.
| Molecular weight | 145.25 |
|---|---|
| Linear formula | [(CH3)2N]3CH |
| Assay | 97% |
| Boiling point | 42-43 °C/12 mmHg(lit.) |
| Density | 0.838 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.436(lit.) |
| Storage temperature | 2-8°C |
| Application | Tris(dimethylamino)methane was used:• to prepare the phosphoramidite derivative of the new nucleoside analog1• as reagent for the introduction of the dimethylaminoethylidene group2 • in ring-opening (RO) polymerization of lactide3 |


Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 11 °C / 51.8 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Tris(dimethylamino)methane used for?
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Tris(dimethylamino)methane is used in chemical synthesis, including the preparation of nucleoside analogs, introduction of the dimethylaminoethylidene group, and in ring-opening polymerisation of lactide.
What are the CAS number and formula for Tris(dimethylamino)methane?
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The CAS number for Tris(dimethylamino)methane is 5762-56-1, and its molecular formula is [(CH3)2N]3CH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Tris(dimethylamino)methane with a minimum assay of 97%. This is a technical/research grade material and is not represented as USP, BP, EP or other pharmacopoeia grades.
How should Tris(dimethylamino)methane be handled safely?
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Tris(dimethylamino)methane is a flammable liquid and causes severe skin burns and eye damage. Handle with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive guidance.
How is Tris(dimethylamino)methane packed, shipped, and exported?
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Tris(dimethylamino)methane is packed and shipped according to international regulations for hazardous materials. As a global supplier, Tech Serve Solutions has extensive experience in exporting chemicals worldwide.
How can I request a sample or quote for Tris(dimethylamino)methane?
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To request a sample or obtain a quote for Tris(dimethylamino)methane, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
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