Triphenylphosphine
Triphenylphosphine (CAS: 603-35-0) is an organophosphorus compound with the formula (C<sub>6</sub>H<sub>5</sub>)<sub>3</sub>P and a molecular weight of 262.29 g/mol. This white crystalline solid is a key reagent in organic synthesis, particularly valued for its role as a ligand in homogeneous catalysis and in various named reactions like the Wittig and Mitsunobu reactions. Its applications span diverse chemical fields, making it a staple in research and industrial settings.
- IUPAC
- Phosphorustriphenyl
- Synonyms
- PhosphorustriphenylTriphenyl phosphinePhenylphosphine, triphenyl-
Ligand in Homogeneous Catalysis
Triphenylphosphine is widely employed as a supporting ligand for transition metal catalysts in homogeneous catalysis. It stabilises metal centres and influences their reactivity in processes such as hydroformylation, hydrogenation, and cross-coupling reactions.
Reagent in Organic Synthesis
It serves as a crucial reagent in several named organic reactions, including the Wittig reaction for alkene synthesis and the Mitsunobu reaction for stereochemical inversion or functional group interconversion.
Precursor for Organophosphorus Compounds
This compound can act as a starting material for the synthesis of other phosphonium salts and organophosphorus derivatives with diverse applications in materials science and pharmaceuticals.
| Molecular weight | 262.29 |
|---|---|
| Linear formula | (C6H5)3P |
| Assay | ≥98.5% (GC) |
| Boiling point | 377 °C(lit.) |
| Vapour pressure | 5 mmHg (20 °C) |
| Vapour density | 9 (vs air) |
| Impurities tested | ~1% triphenylphosphine oxide |
| Melting point | 79-81 °C(lit.)79-81 °C |
Hazard statements
- H302Harmful if swallowed
- H317May cause an allergic skin reaction
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Flash point | 180 °C / 356 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-43-48/20/22 |
| Safety statements (S) | 36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Target Organs | Nervous system |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Triphenylphosphine (CAS: 603-35-0) used for?
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Triphenylphosphine (CAS: 603-35-0) is primarily used as a ligand in homogeneous catalysis and as a reagent in organic synthesis, notably in the Wittig and Mitsunobu reactions.
What is the CAS number and chemical formula for Triphenylphosphine?
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The CAS number for Triphenylphosphine is 603-35-0 and its linear formula is (C₆H₅)₃P.
What grade and purity does Tech Serve Solutions supply for Triphenylphosphine?
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Tech Serve Solutions supplies Triphenylphosphine with an assay of ≥98.5% (GC). We do not represent this product as USP, BP, or EP grade.
How should Triphenylphosphine be handled safely?
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Handle Triphenylphosphine with appropriate personal protective equipment, including a dust mask (N95), eyeshields, face shield, and gloves. It is harmful if swallowed, may cause an allergic skin reaction, and may cause damage to the nervous system through prolonged or repeated exposure (H302, H317, H373).
Is Triphenylphosphine supplied internationally by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Triphenylphosphine.
How can I request a quote or sample for Triphenylphosphine?
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Please contact our sales team or use the online enquiry form to request a quote or sample for Triphenylphosphine.
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